Week 1
| Date | Groupe | Host Team | Score | Away Team |
| 17-09-2019 | E | Napoli | 2-0 Dries Mertens (pen), Fernando Llorente | Liverpool |
| 17-09-2019 | E | Salzburg | 6-2 Erling Haland (3), Hee-Chan Hwang, Dominik Szoboszlai, Andreas Ulmer / Jhon Lucumi, Mbwana Samatta | Genk |
| 17-09-2019 | F | İnter | 1-1 Nicolo Barella / Peter Olayink | Slavia Praha |
| 17-09-2019 | F | Borussia Dortmund | 0-0 | FC Barcelona |
| 17-09-2019 | G | Olympigue Lyon | 1-1 Memphis Depay / Serdar Azmoun | Zenit |
| 17-09-2019 | G | SL Benfica | 1-2 Haris Seferovic / Timo Werner (2) | RB Leipzig |
| 17-09-2019 | H | AFC Ajax | 3-0 Quincy Promes, Edson Alvarez, Nicolas Tagliafic | OSC Lille |
| 17-09-2019 | H | FC Chelsea | 0-1 Rodrigo Moreno | Valencia CF |
| 18-09-2019 | A | Club Brugge | 0-0 | G.Saray |
| 18-09-2019 | A | Paris Saint Germain | 3-0 Angel Di Maria (2), Thomas Meunier | Real Madrid |
| 18-09-2019 | B | Olympiacos | 2-2 Daniel Podence, Mathieu Valbuena / Harry Kane, Lucas Moura | Tottenham Hotspur |
| 18-09-2019 | B | Bayern München | 3-0 Kingsley Coman, Robert Lewandowski, Thomas Muller | Crvena Zvezda |
| 18-09-2019 | C | Dinamo Zagrep | 4-0 Marin Leovac, Mislav Orsic (3) | Atalanta |
| 18-09-2019 | C | Shakhtar Donetsk | 0-3 Riyad Mahrez, Ilkay Gundogan, Gabriel Jesus | Manchester City |
| 18-09-2019 | D | Atletico Madrid | 2-2 Stefan Savic, Hector Herrera / Juan Cuadrado, Blaise Matuidi | Juventus |
| 18-09-2019 | D | Bayer Leverkusen | 1-2 Benedikt Howedes (og) / Grzegorz Krychowiak, Dmitri Barinov | Lokomotif Moscow |
Week 2
| Date | Groupe | Host Team | Score | Away Team |
| 01-10-2019 | A | Real Madrid | 2-2 Sergio Ramos, Casemiro / Emmanuel Dennis (2) | Club Brugge |
| 01-10-2019 | A | Galatasaray | 0-1 Mauro Icardi | Paris Saint Germain |
| 01-10-2019 | B | Crvena Zvezda | 3-1 Milos Vulic, Nemanja Milunovic, Richmond Boakye / Ruben Semedo | Olympiakos |
| 01-10-2019 | B | Tottenham Hotspur | 2-7 Son Heung-Min, Harry Kane / Joshua Kimmich, Robert Lewandowski (2), Serge Gnabry (4) | Bayern München |
| 01-10-2019 | C | Atalanta | 1-2 Duvan Zapata / Junior Moraes, Manor Solomon | Shakhtar Donetsk |
| 01-10-2019 | C | Manchester City | 2-0 Raheem Sterling, Phil Foden | Dinamo Zagrep |
| 01-10-2019 | D | Juventus | 3-0 Gonzalo Higuain, Federico Bernardeschi, Cristiano Ronaldo | Bayer Leverkusen |
| 01-10-2019 | D | Lokomotif Moscow | 0-2 Joao Felix, Thomas Teye Partey | Atletico Madrid |
| 02-10-2019 | E | Liverpool | 4-3 Sadio Mane, Andrew Robertson, Mohamed Salah (2) / Hee-Chan Hwang, Takumi Minamino, Erling Haland | Salzburg |
| 02-10-2019 | E | Genk | 0-0 | Napoli |
| 02-10-2019 | F | Slavia Praha | 0-2 Achraf Hakimi (2) | Borussia Dortmund |
| 02-10-2019 | F | FC Barcelona | 2-1 Luis Suarez (2) / Lautaro Martinez | İnter |
| 02-10-2019 | G | Zenit | 3-1 Artem Dzyuba, Ruben Dias (og), Serdar Azmoun / Raul De Tomas | SL Benfica |
| 02-10-2019 | G | RB Leipzig | 0-2 Memphis Depay, Martin Terrier | Olympigue Lyon |
| 02-10-2019 | H | Valencia CF | 0-3 Hakim Ziyach, Quincy Promes, Donny van de Beek | AFC Ajax |
| 02-10-2019 | H | OSC Lille | 1-2 Tammy Abraham, Willian | FC Chelsea |
Week 3
| Date | Groupe | Host Team | Score | Away Team |
| 22-10-2019 | A | Club Brugge | 0-5 Mauro Icardi (2), Kylian Mbappe (3) | Paris Saint Germain |
| 22-10-2019 | A | Galatasaray | 0-1 Toni Kroos | Real Madrid |
| 22-10-2019 | B | Olympiakos | 2-3 Youseff El Arabi, Guilherme / Robert Lewandowski (2)Corentin Tolisso | Bayern München |
| 22-10-2019 | B | Tottenham | 5-0 Harry Kane (2), Son Heung-Min (2), Erik Lamela | Crvena Zvezda |
| 22-10-2019 | C | Shakhtar Donetsk | 2-2 Yevgen Konoplyanka, Dodo / Dani Olmo, Mislav Orsic (pen) | Dinamo Zagreb |
| 22-10-2019 | C | Manchester City | 5-1 Sergio Aguero (2), Raheem Sterling (3) / Ruslan Malinovskiy | Atalanta |
| 22-10-2019 | D | Atletico Madrid | 1-0 Alvaro Morata | Bayer Leverkusen |
| 22-10-2019 | D | Juventus | 2-1 Paulo Dybala (2) / Aleksey Miranchuk | Lokomotiv Moscow |
| 23-10-2019 | E | Salzburg | 2-3 Erling Haland (2) / Dries Mertens (2), Lorenzo Insigne | Napoli |
| 23-10-2019 | E | Genk | 1-4 Stephen Odey / Alex Oxlade-Chamberlain (2), Sadio Mane, Mohamed Salah | Liverpool |
| 23-10-2019 | F | İnter | 2-0 Lautaro Martinez, Antonio Candreva | Borussia Dortmund |
| 23-10-2019 | F | Slavia Prag | 1-2 Jan Boril / Lionel Andres Messi, Peter Olayinka (og) | FC Barcelona |
| 23-10-2019 | G | RB Leipzig | 2-1 Konrad Laimer, Marcel Sabitzer / Yaroslav Rakitskiy | Zenit |
| 23-10-2019 | G | SL Benfica | 2-1 Rafa Silva, Pizzi / Memphis Depay | Olympigue Lyon |
| 23-10-2019 | H | AFC Ajax | 0-1 Michy Batshuayi | FC Chelsea |
| 23-10-2019 | H | OSC Lille | 1-1 Jonathan Ikone / Denis Cheryshev | Valencia |
Week 4
| Date | Groupe | Host Team | Score | Away Team |
| 06-11-2019 | A | Paris Saint Germain | 1-0 Mauro Icardi | Club Brugge |
| 06-11-2019 | A | Real Madrid | 6-0 Rodrygo (3), Sergio Ramos, Karim Benzema (2) | Galatasaray |
| 06-11-2019 | B | Bayern München | 2-0 Robert Lewandowski, Ivan Perisic | Olympiakos |
| 06-11-2019 | B | Crvena Zvezda | 0-4 Giovani Lo Celso, Son Heung-Min (2), Christian Eriksen | Tottenham |
| 06-11-2019 | C | Dinamo Zagreb | 3-3 Bruno Petkovic, Luka Ivanusec, Arijan Ademi / Alan Patrick, Junior Moraes, Tete | Shakhtar Donetsk |
| 06-11-2019 | C | Atalanta | 1-1 Mario Pasalic / Raheem Sterling | Manchester City |
| 06-11-2019 | D | Bayer Leverkusen | 2-1 Thomas Teye Partey (og), Kevin Volland / Alvaro Morata | Atletico Madrid |
| 06-11-2019 | D | Lokomotiv Moscow | 1-2 Aleksey Miranchuk / Aaron Ramsey, Douglas Costa | Juventus |
| 05-11-2019 | E | Napoli | 1-1 Hirving Lozano / Erling Haland | Salzburg |
| 05-11-2019 | E | Liverpool | 2-1 Georginio Wijnaldum, Alex Oxlade-Chamberlain / Mbwana Samatta | Genk |
| 05-11-2019 | F | Borussia Dortmund | 3-2 Achraf Hakimi (2), Julian Brandt / Lautaro Martinez, Matias Vecino | İnter |
| 05-11-2019 | F | FC Barcelona | 0-0 | Slavia Prag |
| 05-11-2019 | G | Zenit | 0-2 Diego Demme, Marcel Sabitzer | RB Leipzig |
| 05-11-2019 | G | Olympigue Lyon | 3-1 Joachim Andersen, Memphis Depay, Bertrand Traore/ Haris Seferovic | SL Benfica |
| 05-11-2019 | H | FC Chelsea | 4-4 Jorginho (2), Cesar Azpilicueta, Reece James / Tammy Abraham (og), Quincy Promes, Kepa Arrizabalaga (og), Donny van de Beek | AFC Ajax |
| 05-11-2019 | H | Valencia | 4-1 Daniel Parejo, Boubakary Soumare (og), Geoffrey Kondogbia, Ferran Torres / Victor Osimhen | OSC Lille |
Week 5
| Date | Groupe | Host Team | Score | Away Team |
| 26-11-2019 | A | G.Saray | 1-1 Adem Büyük / Charles De Ketelaere | Club Brugge |
| 26-11-2019 | A | Real Madrid | 2-2 Karim Benzema (2) / Kylian Mbappe, Pablo Sarabia | Paris Saint Germain |
| 26-11-2019 | B | Crvena Zvezda | 0-6 Leon Goretzka, Robert Lewandowski (4), Corentin Tolisso | Bayern München |
| 26-11-2019 | B | Tottenham Hotspur | 4-2 Dele Alli, Harry Kane (2), Serge Aurier / Youseff El Arabi, Ruben Semedo | Olympiacos |
| 26-11-2019 | C | Atalanta | 2-0 Luis Muriel, Alejandro Gomez | Dinamo Zagrep |
| 26-11-2019 | C | Manchester City | 1-1 Ilkay Gundogan / Manor Solomon | Shakhtar Donetsk |
| 26-11-2019 | D | Lokomotif Moscow | 0-2 Rifat Zhemaletdinov (og), Sven Bender | Bayer Leverkusen |
| 26-11-2019 | D | Juventus | 1-0 Paulo Dybala | Atletico Madrid |
| 27-11-2019 | E | Liverpool | 1-1 Dejan Lovren / Dries Mertens | Napoli |
| 27-11-2019 | E | RC Genk | 1-4 Mbwana Samatta / Patson Daka, Takumi Minamino, Hee-Chan Hwang, Erling Haland | Salzburg |
| 27-11-2019 | F | Slavia Praha | 1-3 Tomas Soucek / Romelu Lukaku, Lautaro Martinez (2) | İnter |
| 27-11-2019 | F | FC Barcelona | 3-1 Luis Suarez, Lionel Andres Messi, Antoine Griezmann / Jadon Sancho | Borussia Dortmund |
| 27-11-2019 | G | Zenit St.Petersburg | 2-0 Artem Dzyuba, Magomed Ozdoev | Olympigue Lyon |
| 27-11-2019 | G | RB Leipzig | 2-2 Emil Forsberg (2) / Pizzi, Carlos Vinicius | SL B enfica |
| 27-11-2019 | H | Valencia | 2-2 Carlos Soler, Daniel Wass / Mateo Kovacic, Christian Pulisic | Chelsea |
| 27-11-2019 | H | OSC Lille | 0-2 Hakim Ziyach, Quincy Promes | AFC Ajax |
Week 6
| Date | Groupe | Host Team | Score | Away Team |
| 11-12-2019 | A | Club Brugge | 1-3 Hans Vanaken / Rodrygo, Vinicius Junior, Luka Modric | Real Madrid |
| 11-12-2019 | A | Paris Saint Germain | 5-0 Mauro Icardi, Pablo Sarabia, Neymar, Kylian Mbappe, Edinson Cavani | G.Saray |
| 11-12-2019 | B | Olympiacos | 1-0 Youseff El Arabi | Crvena Zvezda |
| 11-12-2019 | B | Bayern München | 3-1 Kingsley Coman, Thomas Muller, Philippe Coutinho / Ryan Sessegnon | Tottenham Hotspur |
| 11-12-2019 | C | Shakhtar Donetsk | 0-3 Timothy Castagne, Mario Pasalic, Robin Gosens | Atalanta |
| 11-12-2019 | C | Dinamo Zagrep | 1-4 Dani Olmo / Gabriel Jesus (3), Phil Foden | Manchester City |
| 11-12-2019 | D | Bayer Leverkusen | 0-2 Cristiano Ronaldo, Gonzalo Higuain | Juventus |
| 11-12-2019 | D | Atletico Madrid | 2-0 Joao Felix, Felipe | Lokomotif Moscow |
| 10-12-2019 | E | Napoli | 4-0 Arkadiusz Milik (3), Dries Mertens | RC Genk |
| 10-12-2019 | E | Salzburg | 0-2 Naby Keita, Mohamed Salah | Liverpool |
| 10-12-2019 | F | İnter | 1-2 Romelu Lukaku / Carles Perez, Ansu Fati | FC Barcelona |
| 10-12-2019 | F | Borussia Dortmund | 2-1 Jadon Sancho, Julian Brandt / Tomas Soucek | Slavia Praha |
| 10-12-2019 | G | Olympigue Lyon | 2-2 Houssem Aouar, Memphis Depay / Emil Forsberg, Timo Werner | RB Leipzig |
| 10-12-2019 | G | SL Benfica | 3-0 Franco Cervi, Douglas Santos Pizzi, Serdar Azmoun (og) | Zenit St.Petersburg |
| 10-12-2019 | H | Chelsea | 2-1 Tammy Abraham, Cesar Azpilicueta / Loic Remy | OSC Lille |
| 10-12-2019 | H | AFC Ajax | 0-1 Rodrigo Moreno | Valencia |