2022 FIFA World Cup Africa qualification
First Round
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Ethiopia | 1-1 | Lesotho | 0–0 | 1-1 Nkau Lerotholi (og) / Tsepo Seturumane |
| Somalia | 2-3 | Zimbabwe | 1-0 Shakunda | 1-3 Omar Mohamed / Marshall Munetsi, Admiral Muskwe, Khama Billiat |
| Eritrea | 1-4 | Namibia | 1–2 Ali Sulieman / Esey Tesfay (og), Peter Shalulile | 0-2 Peter Shalulile, Absalom Limbondi |
| Burundi | 2-2 | Tanzania | 1–1 Cedric Amissi / Simon Msuva | 1-1 Fiston Abdul Razak / Mbwana Samatta (0-3 pen.) |
| Djibouti | 2-1 | Eswatini | 2–1 Mahdi Houssein Mahabeh, Abdi Idleh hamza / Siboniso Mamba | 0-0 |
| Botswana | 0-1 | Malawi | 0-0 | 0-1 Gerald Phiri Jr. |
| Gambia | 1-3 | Angola | 0-1 Wilson | 1-2 Assan Ceesay / Geraldo, Fabio Abreu |
| Liberia | 3-2 | Sierra Leone | 3-1 | 0-1 Kei Kamara |
| Mauritius | 0-3 | Mozambique | 0–1 Telinho | 0-2 Clesio, Catamo |
| São Tomé and Príncipe | 1-3 | Guinea-Bissau | 0–1 Nanu | 1-2 Iniesta / Joseph Mendes (2) |
| South Sudan | 1-2 | Equatorial Guinea | 1–1 Niko Kata (og) / Luis Meseguer | 0-1 Emilio Nsue |
| Comoros | 1-3 | Togo | 1-1 Ibroihim Youssouf / Kodjo Laba | 0-2 Kassim M'Dahoma, Gilles Sunu |
| Chad | 1-3 | Sudan | 1-3 Ezechiel Ndouassel / Ramadan Agab (3) | 0-0 |
| Seychelles | 0-10 | Rwanda | 0-3 Muhadjiri Hakizimana, Yannick Mukunzi, Meddie Kagere | 0-7 Djihad Bizimana, Meddie Kagere (2), Jacgues Tuyisenge (2), Yannick Mukunzi, Hakizimina |
Second Round
Group A
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| Algeria | Advance to third round | ||||||
| Burkina Faso | |||||||
| Niger | |||||||
| Djibouti |
Group B
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| Tunisia | Advance to third round | ||||||
| Zambia | |||||||
| Mauritania | |||||||
| Eguatorial Guinea |
Group C
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| Nigeria | Advance to third round | ||||||
| Cape Verde | |||||||
| Central African Republic | |||||||
| Liberia |
Group D
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| Cameroon | Advance to third round | ||||||
| Ivory Coast | |||||||
| Mozambigue | |||||||
| Malawi |
Group E
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| Mali | Advance to third round | ||||||
| Uganda | |||||||
| Kenya | |||||||
| Rwanda |
Group F
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| Egypt | Advance to third round | ||||||
| Gabon | |||||||
| Libya | |||||||
| Angola |
Group G
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| Ghana | Advance to third round | ||||||
| South Africa | |||||||
| Zimbabwe | |||||||
| Ethiopia |
Group H
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| Senegal | Advance to third round | ||||||
| Congo | |||||||
| Namibia | |||||||
| Togo |
Group I
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| Morocco | Advance to third round | ||||||
| Guinea | |||||||
| Guinea-Bissau | |||||||
| Sudan |
Group J
| Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| DR Congo | Advance to third round | ||||||
| Benin | |||||||
| Madagascar | |||||||
| Tanzania |