Groupe Stage
Groupe A
| Rank | Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| 1 | Florentia | 2 | 2 | 0 | 0 | 5-0 | 6 | Playoffs |
| 2 | Hellas Verona | 2 | 1 | 0 | 1 | 2-1 | 3 | |
| 3 | Cittadella Women | 2 | 0 | 0 | 2 | 0-6 | 0 |
| Date | Venue | Team 1 | Score | Team 2 |
| 27-09-2020 | Cittadella Women | 0-2 Asia Bragonzi, Giorgia Motta | Hellas Verona | |
| 18-11-2020 | Cittadella Women | 0-4 Jonna Dahlberg (2), Melania Martinovic (2) | Florentia | |
| 22-11-2020 | Hellas Verona | 0-1 Melania Martinovic | Florentia |
Groupe B
| Rank | Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| 1 | Inter Women | 2 | 1 | 1 | 0 | 7-3 | 4 | Playoffs |
| 2 | Lazio Women | 2 | 1 | 1 | 0 | 6-4 | 4 | |
| 3 | Brescia | 2 | 0 | 0 | 2 | 1-7 | 0 |
| Date | Venue | Team 1 | Score | Team 2 |
| 27-09-2020 | Brescia | 1-3 Cristina Merli / Noemi Visentin, Adriana Martin Santamaria, Sarah Mattei | Lazio Women | |
| 18-11-2020 | Brescia | 0-4 Stefania Tarenzi, Gloria Marinelli, Caroline-Sophie Moller, Julie Debever | Inter Women | |
| 22-11-2020 | Lazio Women | 3-3 Lipman, Adriana Martin Santamaria (2) / Gloria Marinelli (2), Stefania Tarenzi | Inter Women |
Groupe C
| Rank | Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| 1 | Fiorentina | 2 | 2 | 0 | 0 | 11-2 | 6 | Playoffs |
| 2 | San Marino Academy | 2 | 1 | 0 | 1 | 5-8 | 3 | |
| 3 | Riozzese Como | 2 | 0 | 0 | 2 | 4-10 | 0 |
| Date | Venue | Team 1 | Score | Team 2 |
| 27-09-2020 | Riozzese Como | 3-4 Zhanna Ferrario, Alessia Rognoni (2) / Melissa Nozzi, Giulia Rizzon (og), Millie Chandarana, Raffaella Barbieri | San Marino Academy | |
| 01-11-2020 | Riozzese Como | 1-6 Giulia Ambrosetti / Daniela Sabatino (2), Claudia Neto, Tatiana Bonetti, Martina Piemonte (2) | Fiorentina | |
| 22-11-2020 | San Marino Academy | 1-5 Azzurra Corazzi / Daniela Sabatino (2), Martina Piemonte, Tatiana Bonetti, Sara Baldi | Fiorentina |
Groupe D
| Rank | Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| 1 | Empoli | 2 | 2 | 0 | 0 | 8-2 | 6 | Playoffs |
| 2 | Ravenna Women | 2 | 1 | 0 | 1 | 4-5 | 3 | |
| 3 | Chievo Verona Women | 2 | 0 | 0 | 2 | 1-6 | 0 |
| Date | Venue | Team 1 | Score | Team 2 |
| 27-09-2020 | Chievo Verona Women | 1-2 Silvia Carraro / Giorgia Filippi, Giada Burbassi | Ravenna Women | |
| 18-11-2020 | Chievo Verona Women | 0-4 Cecilia Prugna, Chante Dompig, Angela Caloia (2) | Empoli | |
| 22-11-2020 | Ravenna Women | 2-4 Giada Morucci, Arianna Marengoni / Benedetta Glionna (2), Giorgia Miotto, Norma Cinotti | Empoli |
Groupe E
| Rank | Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| 1 | Juventus | 2 | 2 | 0 | 0 | 9-2 | 6 | Playoffs |
| 2 | Pink Bari | 2 | 0 | 1 | 1 | 2-5 | 1 | |
| 3 | Pomigliano Women | 2 | 0 | 1 | 1 | 2-6 | 1 |
| Date | Venue | Team 1 | Score | Team 2 |
| 27-09-2020 | Pomigliano Women | 1-1 Giuseppina Moraca / Lucia Ceci | Pink Bari | |
| 22-11-2020 | Pink Bari | 1-4 Emelie Helmvall / Barbara Bonansea (2), Maria Aparecida Souza Alves, Annahita Zamanian | Juventus | |
| 13-01-2021 | Pomigliano Women | 1-5 Romina Pinna / Valentina Cernoia, Andrea Staskova (2), Dalila Ippolito, Maria Aparecida Souza Alves | Juventus |
Groupe F
| Rank | Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| 1 | Milan | 2 | 2 | 0 | 0 | 3-0 | 3 | Playoffs |
| 2 | Orobica Bergamo | 2 | 1 | 0 | 1 | 1-4 | 3 | |
| 3 | Cesena | 2 | 0 | 0 | 2 | 0-3 | 0 |
| Date | Venue | Team 1 | Score | Team 2 |
| 27-09-2020 | Cesena | 0-1 Beatrice Airola | Orobica Bergamo | |
| 19-11-2020 | Cesena | 0-2 Giorgia Spinelli, Valentina Giacinti | Milan | |
| 22-11-2020 | Orobica Bergamo | 0-4 Valentina Giacinti (2), Linda Tucceri (2) | Milan |
Groupe G
| Rank | Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| 1 | Sassuolo | 2 | 1 | 1 | 0 | 5-3 | 4 | Playoffs |
| 2 | Napoli | 2 | 1 | 1 | 0 | 2-1 | 4 | |
| 3 | Pontedera | 2 | 0 | 0 | 2 | 2-5 | 0 |
| Date | Venue | Team 1 | Score | Team 2 |
| 27-09-2020 | Pontedera | 0-1 Zoubida El Bastali | Napoli | |
| 19-11-2020 | Pontedera | 2-4 Natasha Carrozzo, Sandy Iannella / Valeria Monterubbiano, Michela Cambiaghi, Mana Mihashi, Alice Pellinghelli | Sassuolo | |
| 22-11-2020 | Napoli | 1-1 Eleonora Goldoni / Erika Santoro | Sassuolo |
Groupe H
| Rank | Team | Pld. | W | D | L | Goals | Pts. | Qualification |
| 1 | AS Roma | 2 | 2 | 0 | 0 | 12-0 | 6 | Playoffs |
| 2 | Roma CF | 2 | 1 | 0 | 1 | 2-7 | 3 | |
| 3 | Tavagnacco | 2 | 0 | 0 | 2 | 0-7 | 0 |
| Date | Venue | Team 1 | Score | Team 2 |
| 27-09-2020 | Roma CF | 2-0 Aurora Miglio, Julia Glaser | Tavagnacco | |
| 22-11-2020 | Tavagnacco | 0-5 Osinachi Ohale, Andrine Hegerberg, Manuela Giugliano, Agnese Bonfantini, Emma Severini | AS Roma | |
| 13-01-2021 | Roma CF | 0-7 A Massa, Alves da Silva Andress (3), Serena Landa, Alice Corelli (2) | AS Roma |