| ROUND 1 | |||
|---|---|---|---|
| 11.09.20 20:00 | Rizespor | 1 - 2 Milan Skoda / Gökhan Gönül, Jose Ernesto Sosa | Fenerbahce |
| 12.09.20 20:00 | Goztepe | 5 - 1 Alpaslan Ozturk, Atinc Nukan, Halil Akbunar, Marcio Mossoro, Zlatko Tripic / Oğuz Yılmaz | Yukatel Denizlispor |
| 12.09.20 20:00 | Galatasaray | 3 - 1 Radamel Falcao (2), Emre Kilinc / Sndre | Gaziantep FK |
| 12.09.20 17:00 | Demir Grup Sivasspor | 0 - 2 Davidson, Steven Caulker | Aytemiz Alanyaspor |
| 12.09.20 17:00 | Fatih Karagumruk AS | 3 - 0 Ervin Zukanovic, Artur Sobiech, Erik Sabo | Yeni Malatyaspor |
| 13.09.20 17:00 | MKE Ankaragucu | 1 - 2 Jonathan Bolingi / Oltan Karakullukcu (2) | Erzurum BB |
| 13.09.20 17:00 | HES Kablo Kayserispor | 1 - 0 Zoran Kvrzic | Kasimpasa |
| 13.09.20 20:00 | Fraport-TAV Antalyaspor | 2 - 0 Bünyamin Balcı, Hakan Ozmert | Genclerbirligi |
| 13.09.20 20:00 | Trabzonspor | 1 - 3 Abdülkadir Ömür / Tyler Boyd, Bernard Mensah, Jeremain Lens | Besiktas |
| 14.09.20 20:00 | Atakaş Hatayspor | 2 - 0 Selim Ilgaz, Helder Barbosa | Medipol Basaksehir FK |
| ROUND 2 | |||
| 18.09.20 20:00 | Yeni Malatyaspor | 1-1 Adem Büyük / Halil Akbunar | Goztepe |
| 19.09.20 13:30 | Genclerbirligi | 0-0 | İttifak Holding Konyaspor |
| 19.09.20 16:00 | Yukatel Denizlispor | 0-0 | Trabzonspor |
| 19.09.20 19:00 | Aytemiz Alanyaspor | 2-0 Adam Bareiro (2) | HES Kablo Kayserispor |
| 19.09.20 19:00 | Besiktas | 1-1 Cyle Larin / Gökdeniz Bayraktar | Fraport-TAV Antalyaspor |
| 20.09.20 13:30 | Erzurum BB | 1-2 Arvydas Novikovas / Arouna Kone, Max Gradel | Demir Grup Sivasspor |
| 20.09.20 16:00 | Kasimpasa | 2-0 Kevin Varga, Alan | Rizespor |
| 20.09.20 19:00 | Gaziantep FK | 2-2 Jean-Armel Kana Biyik, Andre / Ervin Zukanovic, Mevlüt Erdinç | Fatih Karagumruk AS |
| 20.09.20 19:00 | Medipol Basaksehir FK | 0-2 Radamel Falcao, Younes Belhanda | Galatasaray |
| 21.09.20 20:00 | Fenerbahce | 0-0 | Atakaş Hatayspor |
| ROUND 3 | |||
| 25.09.20 20:00 | Fatih Karagumruk AS | 2-0 Enzo Roco, Erik Sabo | Medipol Basaksehir FK |
| 26.09.20 13:30 | HES Kablo Kayserispor | 1-3 Pedro Henrique / Rashad Muhammed, Arvydas Novikovas, Ibrahim Sissoko | Erzurum BB |
| 26.09.20 16:00 | Goztepe | 2-2 Soner Aydogdu, Brown Ideye / Muhammet Demir, Alexandru Maxim | Gaziantep FK |
| 26.09.20 16:00 | Atakaş Hatayspor | 1-0 Mame Diouf | Kasimpasa |
| 26.09.20 19:00 | Trabzonspor | 3-1 Benik Afobe (2), Anthony Nwakaeme / Adem Büyük | Yeni Malatyaspor |
| 27.09.20 13:30 | Rizespor | 1-1 Loic Remy / Mustafa Pektemek | Aytemiz Alanyaspor |
| 27.09.20 16:00 | İttifak Holding Konyaspor | 4-1 Levon Shengelia (2), Artem Kravets (2) / Gökhan Töre | Besiktas |
| 27.09.20 16:00 | Demir Grup Sivasspor | 0-0 | MKE Ankaragucu |
| 27.09.20 19:00 | Galatasaray | 0-0 | Fenerbahce |
| 28.09.20 20:00 | Fraport-TAV Antalyaspor | 1-0 Veysel Sarı | Yukatel Denizlispor |
| ROUND 4 | |||
| 02.10.20 20:00 | MKE Ankaragucu | 0-1 İlhan Parlak | HES Kablo Kayserispor |
| 02.10.20 20:00 | Gaziantep FK | 1-1 Alexandru Maxim / Gaston Campi | Trabzonspor |
| 03.10.20 13:30 | Yeni Malatyaspor | 1-0 Benjamin Tetteh | Fraport-TAV Antalyaspor |
| 03.10.20 16:00 | Erzurum BB | 0-0 | Rizespor |
| 03.10.20 16:00 | Medipol Basakşehir FK | 0-0 | Goztepe |
| 03.10.20 19:00 | Fenerbahce | 2-1 Mbwana Samatta (2) / Erik Sabo | Fatih Karagumruk AS |
| 04.10.20 13:30 | Yukatel Denizlispor | 0-0 | İttifak Holding Konyaspor |
| 04.10.20 16:00 | Aytemiz Alanyaspor | 6-0 Anastasios Bakasetas 18' Davidson (3), Adam Bareiro, Francois Moubandje | Atakaş Hatayspor |
| 04.10.20 16:00 | Besiktas | 0-1 Bogdan Stancu | Genclerbirligi |
| 04.10.20 19:00 | Kasimpasa | 1-0 Yusuf Erdoğan | Galatasaray |
| ROUND 5 | |||
| 17.10.20 20:00 | Çaykur Rizespor | 5-3 Fernando Andrade, Fernando Boldrin, Loic Remy (3) / Joseph Paintsil (2), Torgeir Borven | MKE Ankaragucu |
| 17.10.20 20:00 | İttifak Holding Konyaspor | 1-1 Artem Kravets / Zeki Yavru | Yeni Malatyaspor |
| 17.10.20 20:00 | HES Kablo Kayserispor | 1-3 Wilfried Kanga / Ziya Erdal, Mustapha Yatabare, Faycal Fajr | Demir Grup Sivasspor |
| 17.10.20 20:00 | Trabzonspor | 0-2 İrfan Can Kahveci, Edin Visca | Medipol Basakşehir FK |
| 18.10.20 20:00 | Fraport-TAV Antalyaspor | 1-1 Sidney Sam / Furkan Soyalp | Gaziantep FK |
| 18.10.20 20:00 | Fatih Karagumruk AS | 1-1 Artur Sobiech / Aytac Kara | Kasimpasa |
| 18.10.20 20:00 | Goztepe | 2-3 Guilherme (2) / Jose Sosa, Serdar Aziz, Dimitris Pelkas | Fenerbahce |
| 19.10.20 20:00 | Genclerbirligi | 1-2 Daniel Candeias / Neven Subotic, Hugo Rodallega | Yukatel Denizlispor |
| 19.10.20 20:00 | Galatasaray | 1-2 Radamel Falcao / Khouma Babacar, Davidson | Alanyaspor |
| 09-12-2020 | Atakaş Hatayspor | 3-0 Mame Diouf, Osman Çelik (og), David Akintola | Erzurum BB |
| ROUND 6 | |||
| 23.10.20 21:00 | Kasimpasa A.Ş. | 0-0 | Goztepe |
| 24.10.20 21:00 | Erzurum BB | 1-2 Arvydas Novikovas / Emre Kılınç, Radamel Falcao | Galatasaray |
| 24.10.20 21:00 | Gaziantep FK | 1-0 Muhammet Demir | İttifak Holding Konyaspor |
| 24.10.20 21:00 | Medipol Basakşehir FK | 5-1 Edin Visca (2), Irfan Can Kahveci, Enzo Crivelli, Giuliano / Lukas Podolski | Fraport-TAV Antalyaspor |
| 25.10.20 21:00 | Yeni Malatyaspor | 2-1 Semih Kaya, Kubilay Kanatsızkuş / Murat Yıldırım | Genclerbirligi |
| 25.10.20 21:00 | Aytemiz Alanyaspor | 2-0 Davidson, Khouma Babacar | Fatih Karagumruk AS |
| 25.10.20 21:00 | Fenerbahce | 3-1 Serkan Asan (og), Enner Valencia, Papiss Demba Cisse / Benik Afobe | Trabzonspor |
| 25.10.20 21:00 | Demir Grup Sivasspor | 0-2 Fabricio Baiano, Loic Remy | Çaykur Rizespor |
| 25.10.20 21:00 | Yukatel Denizlispor | 2-3 Muris Mesanovic, Hadi Sacko / Atiba Hutchinson, Vincent Aboubakar, Cyle Larin | Besiktas |
| 15-12-20 14:00 | MKE Ankaragucu | 2-0 Zvonimir Sarlija, Joseph Paintsil | Atakaş Hatayspor |
| ROUND 7 | |||
| 30.10.20 21:00 | Trabzonspor | 3-4 Serkan Asan, Anthony Nwakaeme (2) / Mickael Tirpan, Yusuf Erdogan, Edgar Ie (og), Bengali-Fode Koita | Kasimpasa A.Ş. |
| 30.10.20 21:00 | Fatih Karagumruk AS | 5-1 Lucas Biglia, Badou Ndiaye (2), Alassane Ndao, Erik Sabo / Ricardo Gomes | Erzurum BB |
| 31.10.20 21:00 | Genclerbirligi | 1-1 Daniel Candeias / Alexandru Maxim | Gaziantep FK |
| 31.10.20 21:00 | Galatasaray | 1-0 Ryan Babel | MKE Ankaragucu |
| 01.11.20 21:00 | Besiktas | 1-0 Cyle Larin | Yeni Malatyaspor |
| 01.11.20 21:00 | İttifak Holding Konyaspor | 1-2 Artem Kravets / Marko Jevtovic (og), Danijel Aleksic | Medipol Basakşehir FK |
| 01.11.20 21:00 | Çaykur Rizespor | 1-0 Loic Remy | HES Kablo Kayserispor |
| 02.11.20 21:00 | Fraport-TAV Antalyaspor | 1-2 Lukas Podolski / Ozan Tufan, Diego Perotti | Fenerbahce |
| 02.11.20 21:00 | Atakaş Hatayspor | 1-1 David Akintola / Max Gradel | Demir Grup Sivasspor |
| 09-12-2020 | Goztepe | 1-0 Zlatko Tripic | Aytemiz Alanyaspor |
| ROUND 8 | |||
| 06.11.20 21:00 | Gaziantep FK | 3-1 Kevin Mirallas, Muhammet Demir, Krnan Özer / Cyle Larin | Besiktas |
| 07.11.20 21:00 | Aytemiz Alanyaspor | 1-1 Steven Caulker / Steven Caulker (og) | Trabzonspor |
| 07.11.20 21:00 | Erzurum BB | 1-1 Arvydas Novikovas / Cherif Ndiaye | Goztepe |
| 0711.20 21:00 | Kasimpasa A.Ş. | 2-2 Bengali-Fode Koita, Armin Hodzic / Veysel Sarı, Sidney Sam | Fraport-TAV Antalyaspor |
| 07.11.20 21:00 | Fenerbahce | 0-2 Marko Jevtovic, Artem Kravets | İttifak Holding Konyaspor |
| 08.11.20 21:00 | Medipol Basakşehir FK | 2-1 Fredrik Gulbrandsen, Mehmet Topal / Sefa Yılmaz | Genclerbirligi |
| 08.11.20 21:00 | MKE Ankaragucu | 2-2 Torgeir Borven, Emre Güral / Artur Sobiech, Enzo Roco | Fatih Karagumruk AS |
| 08.11.20 21:00 | HES Kablo Kayserispor | 0-1 Mame Diouf | Atakaş Hatayspor |
| 08.11.20 21:00 | Yeni Malatyaspor | 2-0 Kubilay Kanatsızkus, Afriyie Acquah | Yukatel Denizlispor |
| 08.11.20 21:00 | Demir Grup Sivasspor | 1-2 Caner Osmanpaşa / Younes Belhanda, Arda Turan | Galatasaray |
| ROUND 9 | |||
| 21.11.20 21:00 | Genclerbirligi | 1-5 Diego Angelo / Mert Hakan Yandaş, Diego Perotti (2), Jose Ernesto Sosa, Ozan Tufan | Fenerbahce |
| 21.11.20 21:00 | Fatih Karagumruk AS | 1-1 Erik Sabo / Eric Lichaj (og) | Demir Grup Sivasspor |
| 21.11.20 21:00 | Yukatel Denizlispor | 0-1 Kenan Özer | Gaziantep FK |
| 21.11.20 21:00 | Besiktas | 3-2 Atiba Hutchinson, Cyle Larin, Vincent Aboubakar / Fredrik Gulbrandsen (2) | Medipol Basakşehir FK |
| 22.11.20 21:00 | Fraport-TAV Antalyaspor | 0-2 Salih Uçan, Berkan Kutlu | Aytemiz Alanyaspor |
| 22.11.20 21:00 | Goztepe | 3-1 Cherif Ndiaye (2), Halil Akbunar / Torgeir Borven | MKE Ankaragucu |
| 22.11.20 21:00 | Atakaş Hatayspor | 2-2 Rayane Aabid, Aaron Boupendza / Mame Diouf (og), Fernando Boldrin | Çaykur Rizespor |
| 22.11.20 21:00 | İttifak Holding Konyaspor | 2-1 Nejc Skubic, Musa Çağıran / Aytaç Kara | Kasimpasa A.Ş. |
| 22.11.20 21:00 | Trabzonspor | 1-0 Calub Ekuban | Erzurum BB |
| 23.11.20 21:00 | Galatasaray | 1-1 Mbaye Diagne / Gustavo Campanharo | HES Kablo Kayserispor |
| ROUND 10 | ROUND 10 | ||
| 27.11.20 21:00 | MKE Ankaragucu | 0-1 Lewis Baker | Trabzonspor |
| 28.11.20 21:00 | Medipol Basakşehir FK | 3-3 Fredrik Gulbrandsen 21' Demba Ba / Özer Özdemir, Hugo Rodallega, Radoslaw Murawski | Yukatel Denizlispor |
| 28.11.20 21:00 | Çaykur Rizespor | 0-4 Mbaye Diagne (3), Taylan Antalyalı | Galatasaray |
| 28.11.20 21:00 | Gaziantep FK | 2-2 Kevin Mirallas, Jean-Armel Kana Biyik / Adem Büyük, Jetmir Topalli | Yeni Malatyaspor |
| 29.11.20 21:00 | Kasimpasa A.Ş. | 2-0 Armin Hodzic (2) | Genclerbirligi |
| 29.11.20 21:00 | Erzurum BB | 2-2 Kaan Kanak, Ricardo Gomes / Veysel Sarı, Gokdeniz Bayrakdar | Fraport-TAV Antalyaspor |
| 29.11.20 21:00 | Fenerbahce | 3-4 Papiss Demba Cisse, Ozan Tufan (2) / Vincent Aboubakar (2), Necip Uysal, Fabrice N'Sakala | Besiktas |
| 29.11.20 21:00 | Aytemiz Alanyaspor | 1-0 Khouma Babacar | İttifak Holding Konyaspor |
| 30.11.20 21:00 | Demir Grup Sivasspor | 0-1 Hali Akbunar | Goztepe |
| 30.11.20 21:00 | HES Kablo Kayserispor | 0-0 | Fatih Karagumruk AS |
| ROUND 11 | |||
| 04.12.20 21:00 | Besiktas | 3-0 Bernard Mensah, Atiba Hutchinson, Vincent Aboubakar | Kasimpasa A.Ş. |
| 05.12.20 21:00 | Genclerbirligi | 2-1 Berat Ayberk Ozdemir, Daniel Candeias / Anastasios Bakasetas | Aytemiz Alanyaspor |
| 05.12.20 21:00 | Goztepe | 1-1 Pedro Henrique / Soner Aydoğdu | HES Kablo Kayserispor |
| 05.12.20 21:00 | Yeni Malatyaspor | 1-1 Ponck (og) / Giuliano | Istanbul Basaksehir |
| 05.12.20 21:00 | İttifak Holding Konyaspor | 2-0 Uğur Demirok, Amir Hadziahmetovic | Erzurum BB |
| 05.12.20 21:00 | Galatasaray | 3-0 Mbaye Diagne, Pablo Santos (og), Muhammed Kerem Aktürkoğlu | Atakaş Hatayspor |
| 06.12.20 21:00 | Antalyaspor | 1-0 Adis Jahovic | MKE Ankaragucu |
| 06.12.20 21:00 | Yukatel Denizlispor | 0-2 Papiss Demba Cisse, Gökhan Gönül | Fenerbahce |
| 06.12.20 21:00 | Fatih Karagumruk AS | 2-1 Alassane Ndao (2) / Yassine Meriah | Çaykur Rizespor |
| 06.12.20 21:00 | Trabzonspor | 1-1 Calub Ekuban / Hakan Arslan | Demir Grup Sivasspor |
| ROUND 12 | |||
| 11.12.20 21:00 | Kasimpasa | 3-2 Bengali-Fode Koita (2), Kevin Varga / Recep Niyaz, Hugo Rodallega | Yukatel Denizlispor |
| 12.12.20 21:00 | Atakaş Hatayspor | 3-1 Selim Ilgaz, Aaron Boupendza (2) / Jimmy Durmaz | Fatih Karagumruk AS |
| 12.12.20 21:00 | HES Kablo Kayserispor | 0-0 | Trabzonspor |
| 12.12.20 21:00 | Çaykur Rizespor | 3-2 Fernando Boldrin, Konrad Michalak (2) / YalcIn Kayan, Stefano Napoleoni | Goztepe |
| 12.12.20 21:00 | Fenerbahce | 0-3 Adem Büyük, Umut Bulut, Youssouf Ndayishimiye | Yeni Malatyaspor |
| 12.12.20 21:00 | Ankaragucu | 4-3 Saba Lobzhanidze, Torgeir Borven, Joseph Paintsil, Emre Güral / Uğur Demirok, Deni Milosevic, Nejc Skubic | İttifak Holding Konyaspor |
| 13.12.20 21:00 | Aytemiz Alanyaspor | 2-1 Anastasios Bakasetas (2) / Vincent Aboubakar | Besiktas |
| 13.12.20 21:00 | Erzurum BB | 0-1 Sefa Yılmaz | Genclerbirligi |
| 13.12.20 21:00 | Istanbul Basaksehir | 1-2 Enzo Crivelli / Kevin Mirallas, Muhammet Demir | Gaziantep FK |
| 14.12.20 21:00 | Demir Grup Sivasspor | 0-0 | Antalyaspor |
| ROUND 13 | |||
| 18.12.20 21:00 | Fatih Karagumruk AS | 2-1 Alassane Ndao, Mevlüt Erdinç / Mbaye Diagne | Galatasaray |
| 19.12.20 21:00 | Goztepe | 0-1 Mame Diouf | Atakaş Hatayspor |
| 19.12.20 21:00 | Yeni Malatyaspor | 2-0 Adem Büyük (2) | Kasimpasa |
| 19.12.20 21:00 | Trabzonspor | 2-1 Caleb Ekuban, Djanini Tvaris / Milan Skoda | Çaykur Rizespor |
| 19.12.20 21:00 | Gaziantep FK | 3-1 Amedej Vetrih, Alexandru Maxim, Kenan Özer / Dimitris Pelkas | Fenerbahce |
| 20.12.20 21:00 | Genclerbirligi | 1-1 Berat Ayberk Ozdemir / Saba Lobzhanidze | Ankaragucu |
| 20.12.20 21:00 | Yukatel Denizlispor | 1-0 Hugo Rodallega | Alanyaspor |
| 20.12.20 21:00 | Besiktas | 4-0 Vincent Aboubakar (2), Domogaj Vida, Georges-Kevin Nkoudou | Erzurum BB |
| 21.12.20 21:00 | Antalyaspor | 2-0 Amilton Silva, Fredy | HES Kablo Kayserispor |
| 21.12.20 21:00 | İttifak Holding Konyaspor | 0-1 Faycal Fajr | Demir Grup Sivasspor |
| ROUND 14 | |||
| 22.12.20 21:00 | Atakaş Hatayspor | 0-1 Vitor Hugo | Trabzonspor |
| 22.12.20 21:00 | Galatasaray | 3-1 Emre Kılınç, Arda Turan, Sofiane Feghouli / Soner Aydoğdu | Goztepe |
| 23.12.20 21:00 | Alanyaspor | 1-1 Khouma Babacar / Adem Büyük | Yeni Malatyaspor |
| 23.12.20 21:00 | Erzurum BB | 1-2 Emrah Bassan / Hugo Rodallega (2) | Yukatel Denizlispor |
| 23.12.20 21:00 | Fenerbahce | 4-1 Nazim Sangare, Marcel Tisserand, Luiz Gustavo, Mert Hakan Yandaş / Mahmut Tekdemir | Istanbul Basaksehir |
| 23.12.20 21:00 | Kasimpasa | 0-4 Alexandru Maxim (2), Jefferson, Muhammet Demir | Gaziantep FK |
| 24.12.20 21:00 | HES Kablo Kayserispor | 1-2 Pedro Henrique / Uğur Demirok, Marko Jevtovic | İttifak Holding Konyaspor |
| 24.12.20 21:00 | Çaykur Rizespor | 2-1 Yasin Pehlivan, Milan Skoda / Lukas Podolski | Antalyaspor |
| 24.12.20 21:00 | Ankaragucu | 0-1 Domogaj Vida | Besiktas |
| 24.12.20 21:00 | Demir Grup Sivasspor | 3-1 Max Gradel, Hakan Arslan, Mustapha Yatabare / Arda Kızıldağ | Genclerbirligi |
| ROUND 15 | |||
| 26.12.20 21:00 | Goztepe | 1-1 Cherif Ndiaye / Lucas Biglia | Fatih Karagumruk AS |
| 26.12.20 21:00 | Trabzonspor | 0-2 Arda Turan, Oğulcan Çağlayan | Galatasaray |
| 27.12.20 21:00 | Yeni Malatyaspor | 1-3 Afriyie Acquah / Ricardo Gomes, Mitchell Donald, Gabriel Obertan | Erzurum BB |
| 27.12.20 21:00 | Yukatel Denizlispor | 1-2 Recep Niyaz / Atakan Rıdvan Çankaya, Daniel Lukasik | Ankaragucu |
| 27.12.20 21:00 | Gaziantep FK | 3-1 Nouha Dicko, Muhammet Demir, Alexandru Maxim / Davidson | Alanyaspor |
| 27.12.20 21:00 | Istanbul Basaksehir | 2-2 Nacer Chadli, Edin Visca / Yusuf Erdoğan, Armin Hodzic | Kasimpasa |
| 27.12.20 21:00 | Besiktas | 3-0 Güven Yalçın, Cyle Larin, Oğuzhan Özyakup | Demir Grup Sivasspor |
| 28.12.20 21:00 | İttifak Holding Konyaspor | 1-1 Amir Hadziahmetovic / Tunay Torun | Çaykur Rizespor |
| 28.12.20 21:00 | Genclerbirligi | 3-2 Daniel Candeias, Berat Ayberk Özdemir, Oğuzhan Çapar (k.k.) / Wilfried Kanga, Arda Kızıldağ (k.k.) | HES Kablo Kayserispor |
| 29.12.20 21:00 | Antalyaspor | 0-6 David Akintola, Aaron Boupendza (4), Mirkan Aydın | Atakaş Hatayspor |
| ROUND 16 | |||
| 02.01.2021 | Alanyaspor | 3-0 Adam Bareiro, Francois Moubandje, Tayfur Bingöl | Istanbul Basaksehir |
| 02.01.2021 | Ankaragucu | 3-1 Daniel Lukasi, Joseph Paintsil, Torgeir Borven / Youssouf Ndayishimiye | Yeni Malatyaspor |
| 02.01.2021 | Demir Grup Sivasspor | 2-2 Max Gradel, Faycal Fajr / Hugo Rodallega, Muris Mesanovic | Yukatel Denizlispor |
| 02.01.2021 | Erzurum BB | 1-1 Emrah Başsan / Kevin Mirallas | Gaziantep FK |
| 02.01.2021 | Galatasaray | 0-0 | Antalyaspor |
| 02.01.2021 | Atakaş Hatayspor | 2-1 Aaron Boupendza (2) / Artem Kravets | İttifak Holding Konyaspor |
| 03.01.2021 | Fatih Karagumruk AS | 1-2 Jure Balkovec / Anthony Nwakaeme, Caleb Ekuban | Trabzonspor |
| 03.01.2021 | HES Kablo Kayserispor | 0-2 Georges-Kevin Nkoudou, Ajdin Hasic | Besiktas |
| 03.01.2021 | Çaykur Rizespor | 1-1 Milan Skoda / Soner Dikmen | Genclerbirligi |
| 04.01.2021 | Kasimpasa | 0-3 Mame Thiam (2), Ferdi Kadıoglu | Fenerbahce |
| ROUND 17 | |||
| 05.01.2021 | Gaziantep FK | 2-0 Alexandru Maxim, Enver Cenk Şahin | Ankaragucu |
| 05.01.2021 | Yeni Malatyaspor | 2-2 Moryke Fofana, Benjamin Tetteh / Erdoğan Yeşilyurt, Max Gradel | Demir Grup Sivasspor |
| 05.01.2021 | İttifak Holding Konyaspor | 4-3 Erdon Daci (2), Uğur Demirok, Artem Kravets / Mbaye Diagne (2), Oğulcan Çağlayan | Galatasaray |
| 06.01.2021 | Antalyaspor | 3-1 Hakan Özmert, Gökdeniz Bayrakdar, Eren Albayrak / Jure Balkovec | Fatih Karagumruk AS |
| 06.01.2021 | Besiktas | 6-0 Cyle Larin (6), Oğuzhan Özyakup, Ajdin Hasic | Çaykur Rizespor |
| 06.01.2021 | Yukatel Denizlispor | 0-1 Pedro Henrique | HES Kablo Kayserispor |
| 06.01.2021 | Genclerbirligi | 3-1 Robert Piris (2), Giovanni Sio / Aaron Boupendza | Atakaş Hatayspor |
| 06.01.2021 | Istanbul Basaksehir | 1-0 Fredrik Gulbrandsen | Erzurum BB |
| 06.01.2021 | Trabzonspor | 1-0 Caleb Ekuban | Goztepe |
| 07.01.2021 | Fenerbahce | 2-1 Sinan Gümüş, Dimitris Pelkas / Khouma Babacar | Alanyaspor |
| ROUND 18 | |||
| 09-01-2021 | Demir Grup Sivasspor | 2-1 Hakan Arslan (2) / Alexandru Maxim | Gaziantep FK |
| 09-01-2021 | Goztepe | 0-1 Doğukan Sinik | Antalyaspor |
| 09-01-2021 | HES Kablo Kayserispor | 1-0 Semih Kaya (og) | Yeni Malatyaspor |
| 09-01-2021 | Galatasaray | 6-0 Mbaye Diagne, Younes Belhanda (3), Oğulcan Çağlayan, Ryan Babel | Genclerbirligi |
| 10.01.2021 | Ankaragucu | 1-2 Endri Cekici / Edin Visca, Demba Ba | Istanbul Basaksehir |
| 10.01.2021 | Fatih Karagumruk AS | 2-1 Andrea Bertolacci, Badou Ndiaye / Marko Jevtovic | İttifak Holding Konyaspor |
| 10.01.2021 | Atakaş Hatayspor | 2-2 Aaron Boupendza (2) / Vincent Aboubakar, Cyle Larin | Besiktas |
| 10.01.2021 | Çaykur Rizespor | 1-1 Kemal Rüzgar / Hugo Rodallega | Yukatel Denizlispor |
| 11.01.2021 | Erzurum BB | 0-3 Mert Hakan Yandaş, Dimitris Pelkas, Sinan Gümüş | Fenerbahce |
| 11.01.2021 | Alanyaspor | 1-2 Anastasios Bakasetas / Armin Hodzic, Yusuf Erdoğan | Kasimpasa |
| ROUND 19 | |||
| 15.01.21 21:00 | Genclerbirligi | 1-3 Robert Piris / Lucas Biglia, Alassane Ndao, Artur Sobiech | Fatih Karagumruk AS |
| 16.01.21 21:00 | İttifak Holding Konyaspor | 2-3 Sokol Cikalleshi, Amir Hadziahmetovic / Marko Mihojevic, Peter Zulj (2) | Goztepe |
| 16.01.21 21:00 | Istanbul Basaksehir | 1-1 Danijel Aleksic / Hakan Arslan | Demir Grup Sivasspor |
| 16.01.21 21:00 | Gaziantep FK | 2-1 Zoran Kvrzic (og), Alexandru Maxim / Dimitrios Kolovetsios | HES Kablo Kayserispor |
| 16.01.21 21:00 | Antalyaspor | 1-1 Amilton Silva / Benik Afobe | Trabzonspor |
| 17.01.21 21:00 | Yukatel Denizlispor | 0-2 Muhammet Özkal (og), Mame Diouf | Atakaş Hatayspor |
| 17.01.21 21:00 | Yeni Malatyaspor | 4-1 Kubilay Kanatsizkus (2), Umut Bulut, Mustafa Eskihellac / Milan Skoda | Çaykur Rizespor |
| 17.01.21 21:00 | Besiktas | 2-0 Josef De Souza, Georges-Kevin Nkoudou | Galatasaray |
| 18.01.21 21:00 | Kasimpasa | 1-2 Isaac Thelin / Cenk Ahmet Kılınç, Ricardo Gomes | Erzurum BB |
| 18.01.21 21:00 | Fenerbahce | 3-1 Mame Thiam, Mbwana Samatta, Enner Valencia / Emre Güral | Ankaragucu |
| ROUND 20 | |||
| 19.01.21 21:00 | Goztepe | 4-0 Peter Zulj, Cherif Ndiaye, Halil Akbunar (2) | Genclerbirligi |
| 19.01.21 21:00 | HES Kablo Kayserispor | 2-0 Denis Alibec (2) | Istanbul Basaksehir |
| 19.01.21 21:00 | Trabzonspor | 3-1 Anthony Nwakaeme, Flavio, Djanini Tvaris / Levan Shengelia | İttifak Holding Konyaspor |
| 20.01.21 21:00 | Atakaş Hatayspor | 1-2 Aaron Boupendza / Zeki Yavru, Adem Büyük | Yeni Malatyaspor |
| 20.01.21 21:00 | Çaykur Rizespor | 3-0 Milan Skoda (2), Braian Samudio | Gaziantep FK |
| 20.01.21 21:00 | Galatasaray | 6-1 Emre Akbaba, Sofiane Feghouli, Ryan Donk, Muhammet Özkal (k.k.), Younes Belhanda, Jesse Sekidika / Veton Tusha | Yukatel Denizlispor |
| 21.01.21 21:00 | Erzurum BB | 1-1 Emrah Başsan / Anastasios Bakasetas | Alanyaspor |
| 21.01.21 21:00 | Fatih Karagumruk AS | 1-4 Fabio Borini / Vincent Aboubakar, Bernard Mensah (2), Cyle Larin | Besiktas |
| 21.01.21 21:00 | Demir Grup Sivasspor | 1-1 Mustapha Yatabare / Enner Valencia | Fenerbahce |
| 21.01.21 21:00 | Ankaragucu | 1-0 Florent Hadergjonaj (og) | Kasimpasa |
| ROUND 21 | |||
| 23.01.21 21:00 | Istanbul Basaksehir | 1-1 Mehmet Topal / Braian Samudio | Çaykur Rizespor |
| 23.01.21 21:00 | Genclerbirligi | 1-2 Robert Piris / Djanini Tvaris, Caleb Ekuban | Trabzonspor |
| 24.01.21 21:00 | Besiktas | 2-1 Adem Ljajic, Vincent Aboubakar / Zlatko Tripic | Goztepe |
| 24.01.21 21:00 | Yukatel Denizlispor | 1-2 Mix Diskerud / Fabio Borini, Alassane Ndao | Fatih Karagumruk AS |
| 24.01.21 21:00 | Gaziantep FK | 1-1 Jefferson / Junior Morais (og) | Atakaş Hatayspor |
| 24.01.21 21:00 | İttifak Holding Konyaspor | 0-0 | Antalyaspor |
| 24.01.21 21:00 | Yeni Malatyaspor | 0-1 Ryan Babel | Galatasaray |
| 25.01.21 21:00 | Fenerbahce | 3-0 Mame Thiam, Mbwana Samatta, Papiss Demba Cisse | HES Kablo Kayserispor |
| 25.01.21 21:00 | Kasimpasa | 2-0 Haris Hajradinovic, Aytaç Kara | Demir Grup Sivasspor |
| 25.01.21 21:00 | Alanyaspor | 4-3 Salih Uçan, Anastasios Bakasetas, Khouma Babacar, Francois Moubandje / Joseph Paintsil (2), Aliou Badji | Ankaragucu |
| ROUND 22 | |||
| 29.01.21 21:00 | Gaziantep FK | 1-2 Alexandru Maxim / Henry Onyekuru (2) | Galatasaray |
| 29.01.21 21:00 | Yeni Malatyaspor | 0-0 | Fatih Karagumruk AS |
| 30.01.21 21:00 | Istanbul Basaksehir | 1-5 Mohammed Kamara (og) / Mame Diouf (2), David Akintola, Aaron Boupendza (2) | Atakaş Hatayspor |
| 30.01.21 21:00 | Kasimpasa | 0-1 Uğur Demirok | HES Kablo Kayserispor |
| 30.01.21 21:00 | Fenerbahce | 1-0 Gokhan Akkan (k.k.) | Çaykur Rizespor |
| 31.01.21 21:00 | Alanyaspor | 3-1 Fatih Aksoy, Davidson, Khouma Babacar / Max Gradel | Demir Grup Sivasspor |
| 31.01.21 21:00 | Besiktas | 1-2 Vincent Aboubakar / Francisco Montero (k.k.), Vitor Hugo | Trabzonspor |
| 31.01.21 21:00 | Yukatel Denizlispor | 2-1 Recep Niyaz, Muris Mesanovic / Marko Mihojevic | Goztepe |
| 31.01.21 21:00 | Erzurum BB | 1-0 Cenk Ahmet Kılınç | Ankaragucu |
| 31.01.21 21:00 | Genclerbirligi | 0-1 Sidney Sam | Antalyaspor |
| ROUND 23 | |||
| 02.02.21 21:00 | Atakaş Hatayspor | 1-2 Aaron Boupendza / Mame Thiam, Jean Claude Billong (kk) | Fenerbahce |
| 02.02.21 21:00 | Çaykur Rizespor | 1-1 Doğan Erdoğan / Isaac Thelin | Kasimpasa |
| 02.02.21 21:00 | Galatasaray | 3-0 Henry Onyekuru, Ryan Donk, Mostafa Mohamed | Istanbul Basaksehir |
| 03.02.21 21:00 | Antalyaspor | 1-1 Gokdeniz Bayrakdar / Domagoj Vida | Besiktas |
| 03.02.21 21:00 | Fatih Karagumruk AS | 2-0 Alassane Ndao, Fabio Borini | Gaziantep FK |
| 03.02.21 21:00 | HES Kablo Kayserispor | 1-1 Anton Maglica / Giorgos Tzavellas | Alanyaspor |
| 03.02.21 21:00 | İttifak Holding Konyaspor | 0-0 | Genclerbirligi |
| 03.02.21 21:00 | Demir Grup Sivasspor | 0-0 | Erzurum BB |
| 04.02.21 21:00 | Goztepe | 2-2 Cherif Ndiaye (2) / Stevie Mallan, Ahmed İldiz | Yeni Malatyaspor |
| 04.02.21 21:00 | Trabzonspor | 1-0 Anastasios Bakasetas | Yukatel Denizlispor |
| ROUND 24 | |||
| 06.02.21 21:00 | Istanbul Basaksehir | 0-1 Jimmy Durmaz | Fatih Karagumruk AS |
| 06.02.21 21:00 | Kasimpasa | 1-4 Isaac Thelin / Aaron Boupendza, Rayane Aabid, Abdurrahman Canlı, Mohammed Kamara | Atakaş Hatayspor |
| 06.02.21 21:00 | Alanyaspor | 2-1 Adam Bareiro, Mustafa Pektemek / Montassar Talbi | Çaykur Rizespor |
| 06.02.21 21:00 | Fenerbahce | 0-1 Mostafa Mohamed | Galatasaray |
| 07.02.21 21:00 | Ankaragucu | 1-4 Ahmet Oğuz (k.k.) / Max Gradel, Olarenwaju Kayode, Erdoğan Yeşilyurt, Mustapha Yatabare | Demir Grup Sivasspor |
| 07.02.21 21:00 | Besiktas | 1-0 Valentin Rosier | İttifak Holding Konyaspor |
| 07.02.21 21:00 | Yukatel Denizlispor | 1-1 Hugo Rodallega / Gokdeniz Bayrakdar | Antalyaspor |
| 07.02.21 21:00 | Erzurum BB | 1-1 Aatif Chahechouhe (pen) 28' Yaw Ackah / İlhan Parlak | HES Kablo Kayserispor |
| 08.02.21 21:00 | Gaziantep FK | 2-0 Papy Djilobodji, Kevin Mirallas | Goztepe |
| 08.02.21 21:00 | Yeni Malatyaspor | 0-2 Anastasios Bakasetas, Anthony Nwakaeme | Trabzonspor |
| ROUND 25 | |||
| 12.02.21 21:00 | Çaykur Rizespor | 0-2 Aatif Chahechouhe, Oltan Karakullukçu | Erzurum BB |
| 13.02.21 21:00 | Fatih Karagumruk AS | 1-2 Fabio Borini / Mame Thiam, Enner Valencia | Fenerbahce |
| 13.02.21 21:00 | HES Kablo Kayserispor | 0-0 | Ankaragucu |
| 13.02.21 21:00 | Trabzonspor | 1-0 Anastasios Bakasetas | Gaziantep FK |
| 14.02.21 21:00 | Galatasaray | 2-1 Muhammed Kerem Aktürkoğlu, Mostafa Mohamed / Isaac Thelin | Kasimpasa |
| 14.02.21 21:00 | Goztepe | 2-1 Soner Aydogdu, Peter Zulj / Deniz Turuc | Istanbul Basaksehir |
| 14.02.21 21:00 | Atakaş Hatayspor | 0-0 | Alanyaspor |
| 14.02.21 21:00 | İttifak Holding Konyaspor | 2-0 Abdulkerim Bardakçı, Jesse Sekidika | Yukatel Denizlispor |
| 15.02.21 21:00 | Genclerbirligi | 0-3 Rachid Ghezzal, Cenk Tosun (2) | Besiktas |
| 15.02.21 21:00 | Antalyaspor | 1-1 Dever Orgill / Dever Orgill (og) | Yeni Malatyaspor |
| ROUND 26 | |||
| 19.02.21 21:00 | Istanbul Basaksehir | 0-1 Yusuf Sarı | Trabzonspor |
| 20.02.21 21:00 | Alanyaspor | 0-1 Emre Kılınç | Galatasaray |
| 20.02.21 21:00 | Kasimpasa | 3-2 Isaac Thelin, Yusuf Erdogan (2) / Enzo Roco, Lucas Castro | Fatih Karagumruk AS |
| 20.02.21 21:00 | Yeni Malatyaspor | 2-3 Adem Büyük (2) / Ismael Diomande, Sokol Cikalleshi (2) | İttifak Holding Konyaspor |
| 20.02.21 21:00 | Yukatel Denizlispor | 1-0 Muris Mesanovic | Genclerbirligi |
| 21.02.21 21:00 | Erzurum BB | 1-3 Oltan Karakullukcu / Alexandros Katranis, Mame Diouf, Aaron Boupendza | Atakaş Hatayspor |
| 21.02.21 21:00 | Fenerbahce | 0-1 Halil Akbunar | Goztepe |
| 21.02.21 21:00 | Gaziantep FK | 0-0 | Antalyaspor |
| 21.02.21 21:00 | Demir Grup Sivasspor | 2-0 Mustapha Yatabare, Max Gradel | HES Kablo Kayserispor |
| 22.02.21 21:00 | Ankaragucu | 1-1 Torgeir Borven / Godfred Donsah | Çaykur Rizespor |
| ROUND 27 | |||
| 26.02.21 21:00 | Genclerbirligi | 1-1 Ertaç Özbir (k.k.) / Benjamin Tetteh | Yeni Malatyaspor |
| 26.02.21 21:00 | Besiktas | 3-0 Cyle Larin, Vincent Aboubakar, Adem Ljajic | Yukatel Denizlispor |
| 26.02.21 21:00 | Konyaspor | 0-0 | Gaziantep FK |
| 27.02.21 21:00 | Antalyaspor | 0-0 | Istanbul Basaksehir |
| 27.02.21 21:00 | Fatih Karagumruk AS | 2-0 Alassane Ndao, Fabio Borini | Alanyaspor |
| 27.02.21 21:00 | Galatasaray | 2-0 Mostafa Mohamed (2) | Erzurum BB |
| 27.02.21 21:00 | Atakaş Hatayspor | 4-1 Mame Diouf (2), David Akintola (2) / Torgeir Borven | Ankaragucu |
| 27.02.21 21:00 | Çaykur Rizespor | 0-0 | Demir Grup Sivasspor |
| 28.02.21 21:00 | Goztepe | 1-0 Cherif Ndiaye | Kasimpasa |
| 28.02.21 21:00 | Trabzonspor | 0-1 Dimitris Pelkas | Fenerbahce |
| ROUND 28 | |||
| 02.03.21 21:00 | Gaziantep FK | 2-1 Kenan Özer, Jefferson / Sandro Lima | Genclerbirligi |
| 02.03.21 21:00 | Yeni Malatyaspor | 0-1 Atiba Hutchinson | Besiktas |
| 03.03.21 21:00 | Ankaragucu | 2-1 Ibrahim Akdağ, Saba Lobzhanidze / Muhammed Kerem Akturkoglu | Galatasaray |
| 03.03.21 21:00 | Erzurum BB | 2-2 Aatif Chahechouhe, Osman Çelik / Artur Sobiech, Lucas Castro | Fatih Karagumruk AS |
| 03.03.21 21:00 | Istanbul Basaksehir | 1-1 Demba Ba / Sokol Cikalleshi | Konyaspor |
| 03.03.21 21:00 | Kayserispor | 2-1 Karlo Muhar, İlhan Parlak / Braian Samudio | Çaykur Rizespor |
| 03.03.21 21:00 | Demir Grup Sivasspor | 1-1 Mustapha Yatabare / Mame Diouf | Atakaş Hatayspor |
| 04.03.21 21:00 | Fenerbahce | 1-1 Enner Valencia / Fredy | Antalyaspor |
| 04.03.21 21:00 | Kasimpasa | 1-2 Yusuf Erdoğan / Djanini Tvaris, Anastasios Bakasetas | Trabzonspor |
| 04.03.21 21:00 | Alanyaspor | 1-1 Giorgos Tzavellas / Fatih Aksoy (k.k.) | Goztepe |
| ROUND 29 | |||
| 06.03.21 21:00 | Yukatel Denizlispor | 3-2 Hugo Rodallega, Recep Niyaz, Hadi Sacko / Benjamin Tetteh, Stevie Mallan | Yeni Malatyaspor |
| 06.03.21 21:00 | Besiktas | 2-1 Vincent Aboubakar (2) / Nouha Dicko | Gaziantep FK |
| 07.03.21 21:00 | Fatih Karagumruk AS | 0-1 Alper Potuk | Ankaragucu |
| 07.03.21 21:00 | Galatasaray | 2-2 Radamel Falcao (2) / Max Gradel, Tyler Boyd | Demir Grup Sivasspor |
| 07.03.21 21:00 | Genclerbirligi | 0-1 Demba Ba | Istanbul Basaksehir |
| 07.03.21 21:00 | Atakaş Hatayspor | 1-3 Pablo Santos / İlhan Parlak, Uğur Demirok, Pedro Henrique | Kayserispor |
| 08.03.21 21:00 | Konyaspor | 0-3 Attila Szalai, Bright Osayi-Samuel, Serdar Aziz | Fenerbahce |
| 08.03.21 21:00 | Goztepe | 3-1 Leo Schwechlen (og), HalilAkbunar, Alpaslan Öztürk / Emrah Başsan | Erzurum BB |
| 08.03.21 21:00 | Trabzonspor | 1-3 Anastasios Bakasetas / Mustafa Pektemek, Davidson (2) | Alanyaspor |
| 08.03.21 21:00 | Fraport-TAV Antalyaspor | 1-1 Hakan Özmert / Isaac Thelin | Kasimpasa |
| ROUND 30 | |||
| 12.03.21 21:00 | Istanbul Basaksehir | 2-3 Deniz Türüç, Demba Ba / Cyle Larin, Welinton, Josef De Souza | Besiktas |
| 13.03.21 21:00 | Alanyaspor | 4-0 Khouma Babacar, Mustafa Pektemek, Efkan Bekiroğlu, Ceyhun Gulselam | Fraport-TAV Antalyaspor |
| 13.03.21 21:00 | Demir Grup Sivasspor | 1-0 Hakan Arslan | Fatih Karagumruk AS |
| 13.03.21 21:00 | Rizespor | 1-0 Fernando Boldrin | Atakaş Hatayspor |
| 13.03.21 21:00 | Kayserispor | 0-3 Radamel Falcao, Henry Onyekuru (2) | Galatasaray |
| 14.03.21 21:00 | Ankaragucu | 3-0 Torgeir Borven (2), Endri Cekici | Goztepe |
| 14.03.21 21:00 | Erzurum BB | 0-0 | Trabzonspor |
| 14.03.21 21:00 | Fenerbahce | 1-2 Filip Novak / Serdar Aziz (og), Floyd Ayite | Genclerbirligi |
| 14.03.21 21:00 | Gaziantep FK | 2-0 Nouha Dicko, Muhammet Demir | Yukatel Denizlispor |
| 15.03.21 21:00 | Kasimpasa | 1-1 Haris Hajradinovic / Artem Kravets | Konyaspor |
| ROUND 31 | |||
| 19.03.21 21:00 | Galatasaray | 3-4 DeAndre Yedlin, Emre Akbaba, Yassine Meriah (og) / Braian Samudio, Fernando Boldrin (2), Milan Skoda | Rizespor |
| 19.03.21 21:00 | Fatih Karagumruk AS | 3-0 Jimmy Durmaz, Lucas Castro, Artur Sobiech | Kayserispor |
| 20.03.21 21:00 | Genclerbirligi | 2-1 Sefa Yilmaz (2) / Yusuf Erdogan | Kasimpasa |
| 20.03.21 21:00 | Yeni Malatyaspor | 2-2 Günay Güvenç (k.k.), Adem Büyük / Muhammet Demir, Kenan Özer | Gaziantep FK |
| 20.03.21 21:00 | Trabzonspor | 4-1 Caleb Ekuban (2), Djanini Tvaris, Edgar Ie / İbrahim Akdağ | Ankaragucu |
| 20.03.21 21:00 | Goztepe | 3-5 Cherif Ndiaye, Titi, Fousseni Diabate / Mustapha Yatabare (2), Faycal Fajr, Tyler Boyd (2) | Demir Grup Sivasspor |
| 21.03.21 21:00 | Fraport-TAV Antalyaspor | 3-1 Fredy, Gokdeniz Bayrakdar, Bunyamin Balcı / Aatif Chahechouhe | Erzurum BB |
| 21.03.21 21:00 | Besiktas | 1-1 Domagoj Vida / Ozan Tufan | Fenerbahce |
| 21.03.21 21:00 | Yukatel Denizlispor | 0-0 | Istanbul Basaksehir |
| 21.03.21 21:00 | Konyaspor | 1-0 Sokol Cikalleshi | Alanyaspor |
| ROUND 32 | |||
| 03.04.21 20:00 | Atakaş Hatayspor | 3-0 Mame Diouf (2), Ruben Ribeiro | Galatasaray |
| 03.04.21 20:00 | Rizespor | 0-0 | Fatih Karagumruk AS |
| 03.04.21 20:00 | Demir Grup Sivasspor | 0-0 | Trabzonspor |
| 03.04.21 20:00 | Kayserispor | 1-1 İlhan Parlak / Adis Jahovic | Goztepe |
| 04.04.21 20:00 | Alanyaspor | 1-2 Berkan Kutlu / Mattias Johansson, Bogdan Stancu | Genclerbirligi |
| 04.04.21 20:00 | Ankaragucu | 1-0 Torgeir Borven | Fraport-TAV Antalyaspor |
| 04.04.21 20:00 | Erzurum BB | 1-2 Da Costa Manuel / Deni Milosevic, Abdülkerim Bardakçı | Konyaspor |
| 04.04.21 20:00 | Istanbul Basaksehir | 3-1 Tolga Ciğerci, Ömer Ali Şahiner, Danijel Aleksic / Adem Büyük | Yeni Malatyaspor |
| 04.04.21 20:00 | Kasimpasa | 1-0 Aytac Kara | Besiktas |
| 05.04.21 20:00 | Fenerbahce | 1-0 Mbwana Samatta | Yukatel Denizlispor |
| ROUND 33 | |||
| 06.04.21 20:00 | Fatih Karagumruk AS | 1-0 Artur Sobiech | Atakaş Hatayspor |
| 06.04.21 20:00 | Goztepe | 2-0 Halil Akbunar, Cherif Ndiaye | Rizespor |
| 06.04.21 20:00 | Trabzonspor | 1-1 Anastasios Bakasetas / Muğdat Çelik | Kayserispor |
| 07.04.21 20:00 | Fraport-TAV Antalyaspor | 2-4 Fredy (2) / Tyler Boyd (2), Mustapha Yatabare, Erdoğan Yeşilyurt | Demir Grup Sivasspor |
| 07.04.21 20:00 | Besiktas | 3-0 Cenk Tosun, Rachid Ghezzal, Georges-Kevin Nkoudou | Alanyaspor |
| 07.04.21 20:00 | Genclerbirligi | 1-1 Sandro Lima / Da Costa Manuel | Erzurum BB |
| 07.04.21 20:00 | Konyaspor | 1-1 Levan Shengelia / Aliou Badji | Ankaragucu |
| 08.04.21 20:00 | Yukatel Denizlispor | 1-1 Hugo Rodallega / Kevin Varga | Kasimpasa |
| 08.04.21 20:00 | Gaziantep FK | 2-0 Alexandru Maxim (2) | Istanbul Basaksehir |
| 08.04.21 20:00 | Yeni Malatyaspor | 1-1 Mustafa Eskihellac / Enner Valencia | Fenerbahce |
| ROUND 34 | |||
| 10.04.21 20:00 | Rizespor | 0-0 | Trabzonspor |
| 10.04.21 20:00 | Atakaş Hatayspor | 2-3 Mame Diouf (2) / Adis Jahovic (3) | Goztepe |
| 10.04.21 20:00 | Galatasaray | 1-1 Ryan Babel / Alassane Ndao | Fatih Karagumruk AS |
| 11.04.21 20:00 | Ankaragucu | 2-1 Emre Güral, Arda Kizildag (og) / Bogdan Stancu | Genclerbirligi |
| 11.04.21 20:00 | Erzurum BB | 2-4 Leo Schwechlen, Emrah Başsan / Cyle Larin, Oğuzhan Özyakup, Rachid Ghezzal, Georges-Kevin Nkoudou | Besiktas |
| 11.04.21 20:00 | Kayserispor | 0-1 Naldo | Fraport-TAV Antalyaspor |
| 11.04.21 20:00 | Demir Grup Sivasspor | 3-1 Mustapha Yatabare, Olarenwaju Kayode, Robin Yalçın / Zymer Bytyqi | Konyaspor |
| 12.04.21 20:00 | Kasimpasa | 0-0 | Yeni Malatyaspor |
| 12.04.21 20:00 | Fenerbahce | 3-1 Mert Hakan Yandaş, Enner Valenvia, Sinan Gümüş / Alexandru Maxim | Gaziantep FK |
| 12.04.21 20:00 | Alanyaspor | 3-2 Berkan Kutlu, Efkan Bekiroglu, Mustafa Pektemek / Marvin Bakalorz, Veton Tusha | Yukatel Denizlispor |
| ROUND 35 | |||
| 16.04.21 20:00 | Fraport-TAV Antalyaspor | 2-3 Veysel Sarı, Naldo / İsmail Köybaşı, Fernando Boldrin, Erik Sabo | Rizespor |
| 16.04.21 20:00 | Genclerbirligi | 2-3 Diego Angelo, Mattias Johansson / Jorge Felix, Olarenwaju Kayode, Pierre-Yves Polomat (og) | Demir Grup Sivasspor |
| 16.04.21 20:00 | Konyaspor | 0-0 | Kayserispor |
| 16.04.21 20:00 | Besiktas | 2-2 Ante Kulusic (2) / Joseph Paintsil (2) | Ankaragucu |
| 17.04.21 20:00 | Yukatel Denizlispor | 2-3 Hugo Rodallega (2) / Emrah Başsan, Elbasan Rashani (2) | Erzurum BB |
| 17.04.21 20:00 | Goztepe | 1-3 Fousseni Diabate / Muhammed Kerem Aktürkoğlu (3) | Galatasaray |
| 17.04.21 20:00 | Trabzonspor | 1-1 Djanini Tvaris / Aaron Boupendza | Atakaş Hatayspor |
| 17.04.21 20:00 | Hellenex Yeni Malatyaspor | 1-0 Teenage Hadebe | Alanyaspor |
| 18.04.21 20:00 | Gaziantep FK | 2-2 Nouha Dicko, Muhammet Demir / Isaac Thelin (2) | Kasimpasa |
| 18.04.21 20:00 | Istanbul Basaksehir | 1-2 Ömer Ali Şahiner / Attila Szalai, Dimitris Pelkas | Fenerbahce |
| ROUND 36 | |||
| 20.04.21 20:00 | Atakaş Hatayspor | 3-2 Aaron Boupendza (2), Mame Diouf / Amilton Silva, Fredy | Fraport-TAV Antalyaspor |
| 20.04.21 20:00 | Kayserispor | 2-2 Pedro Henrique, İlhan parlak / Robert Piris, Bogdan Stancu | Genclerbirligi |
| 20.04.21 20:00 | Demir Grup Sivasspor | 0-0 | Besiktas |
| 20.04.21 20:00 | Rizespor | 5-3 Damjan Djokovic, Konrad Michalak, Loic Remy, Braian Samudio, Adil Demirbağ (k.k.) / Guilherme, Sokol Cikalleshi, Artem Kravets | Konyaspor |
| 20.04.21 20:00 | Fatih Karagumruk AS | 1-1 Mevlut Erdinç / Berkan Emir | Goztepe |
| 21.04.21 20:00 | Ankaragucu | 1-1 Stelios Kitsiou / Hugo Rodallega | Yukatel Denizlispor |
| 21.04.21 20:00 | Erzurum BB | 1-0 Gabriel Obertan | Hellenex Yeni Malatyaspor |
| 21.04.21 20:00 | Galatasaray | 1-1 Emre Akbaba / Edgar Ie | Trabzonspor |
| 22.04.21 20:00 | Kasimpasa | 0-1 Nacer Chadli | Istanbul Basaksehir |
| 22.04.21 20:00 | Alanyaspor | 3-2 Mustafa Pektemek (2), Steven Caulker / Muhammet Demir (2) | Gaziantep FK |
| ROUND 37 | |||
| 23.04.21 20:00 | Genclerbirligi | 2-1 Mattias Johansson, Giovanni Sio / Braian Samudio | Rizespor |
| 24.04.21 20:00 | Fraport-TAV Antalyaspor | 0-1 Mostafa Muhamed | Galatasaray |
| 24.04.21 20:00 | Besiktas | 3-1 Rachid Ghezzal, Georges-Kevin Nkoudou (2) / Pedro Henrique | Kayserispor |
| 24.04.21 20:00 | Konyaspor | 0-0 | Hatayspor |
| 24.04.21 20:00 | Trabzonspor | 2-0 Djanini Tvaris (2) | Fatih Karagumruk AS |
| 24.04.21 20:00 | Yukatel Denizlispor | 1-1 Mix Diskerud / Olarenwaju Kayode | Demir Grup Sivasspor |
| 25.04.21 20:00 | Gaziantep FK | 2-3 Muhammet Demir (2) / Ricardo Gomes, Hasan Hatipoğlu, Rahman Buğra Çağıran | Erzurum BB |
| 25.04.21 20:00 | Istanbul Basaksehir | 0-0 | Alanyaspor |
| 25.04.21 20:00 | Hellenex Yeni Malatyaspor | 2-1 Adem Büyük, Benjamin Tetteh / Joseph Paintsil | Ankaragucu |
| 25.04.21 20:00 | Fenerbahce | 3-2 Enner Valencia (2), Attila Szalai / Haris Hajradinovic, Florent Hadergjonaj | Kasimpasa |
| ROUND 38 | |||
| 27.04.21 20:00 | Atakaş Hatayspor | 3-1 Rayane Aabid, Mame Diouf (2) / Robert Piris | Genclerbirligi |
| 28.04.21 20:00 | Goztepe | 1-1 Adis Jahovic / Caleb Ekuban | Trabzonspor |
| 28.04.21 20:00 | Fatih Karagumruk AS | 2-2 Eren Albayrak (og), Fabio Borini / Fredy, Amilton Silva | Fraport-TAV Antalyaspor |
| 28.04.21 20:00 | Galatasaray | 1-0 Emre Akbaba | Konyaspor |
| 28.04.21 20:00 | Rizespor | 2-3 İsmail Köybaşı, Damjan Djokovic / Georges-Kevin Nkoudou, Gokhan Töre, Rachid Ghezzal | Besiktas |
| 28.04.21 20:00 | Kayserispor | 6-3 İlhan Parlak (2), Daniel Avramovski (2), Nehuen Paz, Melih Okutan / Angelo Sagal, Muris Mesanovic, Sakıp Aytaç | Yukatel Denizlispor |
| 29.04.21 20:00 | Ankaragucu | 0-1 Andre Sousa | Gaziantep FK |
| 29.04.21 20:00 | Erzurum BB | 1-2 Emrah Başsan / Nacer Chadli, Fredrik Gulbrandsen | Istanbul Basaksehir |
| 29.04.21 20:00 | Demir Grup Sivasspor | 1-0 Jorge Felix | Hellenex Yeni Malatyaspor |
| 29.04.21 20:00 | Alanyaspor | 0-0 | Fenerbahce |
| ROUND 39 | |||
| 01.05.21 20:00 | Besiktas | 7-0 David Akintola (og), Cyle Larin (4), Georges-Kevin Nkoudou, Rıdvan Yılmaz | Atakaş Hatayspor |
| 02.05.21 20:00 | Fraport-TAV Antalyaspor | 2-3 Fredy, Lukas Podolski / Anderson Esiti, Adis Jahovic, Atınç Nukan | Goztepe |
| 02.05.21 20:00 | Yukatel Denizlispor | 0-1 Braian Samudio | Rizespor |
| 02.05.21 20:00 | Konyaspor | 5-1 Ahmet Çalık, Sokol Cikalleshi (2), Zymer Bytyqi, Levan Shengelia / Jeremain Lens | Fatih Karagumruk AS |
| 02.05.21 20:00 | Genclerbirligi | 0-2 Halil Dervişoğlu, Emre Akbaba | Galatasaray |
| 03.05.21 20:00 | Fenerbahce | 3-1 Jose Sosa, Enner Valencia, Dimitris Pelkas / Özgur Sert | Erzurum BB |
| 03.05.21 20:00 | Gaziantep FK | 0-1 Max Gradel | Demir Grup Sivasspor |
| 03.05.21 20:00 | Istanbul Basaksehir | 2-1 Danijel Aleksic, Junior Fernandes / Joseph Paintsil | Ankaragucu |
| 03.05.21 20:00 | Kasimpasa | 3-0 Haris Hajradinovic (2), Isaac Thelin | Alanyaspor |
| 03.05.21 20:00 | Hellenex Yeni Malatyaspor | 1-1 Adem Büyük / İlhan Parlak | Kayserispor |
| ROUND 40 | |||
| 08.05.21 20:30 | Ankaragucu | 1-2 Alper Potuk / Ozan Tufan, Enner Valencia | Fenerbahce |
| 08.05.21 20:30 | Erzurum BB | 0-1 Kevin Varga | Kasimpasa |
| 08.05.21 20:30 | Fatih Karagumruk AS | 5-1 Ervin Zukanovic, Fabio Borini, Alassane Ndao (2), Jeremain Lens / İlker Karakaş | Genclerbirligi |
| 08.05.21 20:30 | Galatasaray | 3-1 Ryan Babel, Radamel Falcao, Arda Turan / Rachid Ghezzal | Besiktas |
| 08.05.21 20:30 | Goztepe | 0-1 Marko Jevtovic | Konyaspor |
| 08.05.21 20:30 | Atakaş Hatayspor | 1-0 Aaron Boupendza | Yukatel Denizlispor |
| 08.05.21 20:30 | Kayserispor | 0-0 | Gaziantep FK |
| 08.05.21 20:30 | Rizespor | 0-4 Adem Büyük, Teenage Hadebe, Moryke Fofana, Kubilay Kanatsizkus | Hellenex Yeni Malatyaspor |
| 08.05.21 20:30 | Demir Grup Sivasspor | 0-0 | Istanbul Basaksehir |
| 08.05.21 20:30 | Trabzonspor | 2-1 Anthony Nwakaeme, Abdulkadir Ömür / Amilton Silva | Fraport-TAV Antalyaspor |
| ROUND 41 | |||
| 12.05.21 20:00 | Alanyaspor | 2-3 Efecan Karaca (2) / Giorgos Tzavellas (og), Elbasan Rashani, Cenk Ahmet Kılıç | Erzurum BB |
| 12.05.21 20:00 | Besiktas | 1-2 Rachid Ghezzal / Andrea Bertolacci, Fabio Borini | Fatih Karagumruk AS |
| 12.05.21 20:00 | Yukatel Denizlispor | 1-4 Recep Niyaz / Halil Dervişoğlu, Ryan Babel, Mostafa Mohamed (2) | Galatasaray |
| 12.05.21 20:00 | Fenerbahce | 1-2 Papiss Demba Cisse / Olarenwaju Kayode, Hakan Arslan | Demir Grup Sivasspor |
| 12.05.21 20:00 | Gaziantep FK | 4-5 Alexandru Maxim, Muhammet Demir (2), Papy Djilobodji / Tunay Torun, Ismail Koybaşı, Alexander, Soderlund, Erik Sabo, Braian Samudio | Rizespor |
| 12.05.21 20:00 | Genclerbirligi | 5-3 Diego Angelo, Floyd Ayite, Bogdan Stancu (2), Metehan Mert / Brown Ideye, Yalçın Kayan, Beykan Simsek | Goztepe |
| 12.05.21 20:00 | Istanbul Basaksehir | 0-0 | Kayserispor |
| 12.05.21 20:00 | Kasimpasa | 3-1 Florent Hadergjonaj, Anıl Koç, Mehmet Yıldırım / Aliou Badji | Ankaragucu |
| 12.05.21 20:00 | Konyaspor | 1-1 Amir Hadziahmetovic / Lewis Baker | Trabzonspor |
| 12.05.21 20:00 | Hellenex Yeni Malatyaspor | 1-1 Adem Büyük / Mame Diouf | Atakaş Hatayspor |
| ROUND 42 | |||
| 15.05.21 | Ankaragucu | 0-1 Davidson | Alanyaspor |
| 15.05.21 | Fraport-TAV Antalyaspor | 0-0 | Konyaspor |
| 15.05.21 | Fatih Karagumruk AS | 5-1 Fabio Borini, Artur Sobiech (2), Jeremain Lens, Vegar Hedenstad / Muris Mesanovic | Yukatel Denizlispor |
| 15.05.21 | Galatasaray | 3-1 Halil Dervişoğlu, Ryan Babel, Oğulcan Çağlayan / Adem Büyük | Hellenex Yeni Malatyaspor |
| 15.05.21 | Goztepe | 1-2 Alparslan Öztürk / Domagoj Vida, Rachid Ghezzal | Besiktas |
| 15.05.21 | Atakaş Hatayspor | 0-1 Jefferson | Gaziantep FK |
| 15.05.21 | Kayserispor | 1-2 Pedro Henrique / Serdar Aziz, Enner Valencia | Fenerbahce |
| 15.05.21 | Rizespor | 0-2 Danijel Aleksic (2) | Istanbul Basaksehir |
| 15.05.21 | Demir Grup Sivasspor | 2-1 Olarenwaju Kayode, Max Gradel / Yusuf Erdogan | Kasimpasa |
| 15.05.21 | Trabzonspor | 2-1 Caleb Ekuban, Benik Afobe / Floyd Ayite | Genclerbirligi |
