| ROUND 1 | |||
|---|---|---|---|
| 12.09.20 | Eibar | 0-0 | Celta Vigo |
| 12.09.20 | Granafa CF | 2-0 Yangel Herrera, Luis Milla | Athletic Club |
| 12.09.20 | Cadiz CF | 0-2 Adrian Lopez, Ruben Garcia | Osasuna |
| 13.09.20 | Alaves | 0-1 Cristian Tello | Real Betis |
| 13.09.20 | Valladolid | 1-1 Michel / Roberto Lopez | Real Sociedad |
| 13.09.20 | Villarreal | 1-1 Gerard Moreno / Pablo Maffeo | Huesca |
| 13.09.20 | Valencia | 4-2 Gabriel Paulista, Maxi Gomez, Manu Vallejo (2) / Jose Luis Morales (2) | Levante |
| 12.01.21 | Atletico Madrid | 2-0 Angel Correa, Saul | Sevilla |
| 09.02.21 | Real Madrid | 2-0 Karim Benzema, Ferland Mendy | Getafe |
| 24.02.21 | Barcelona | 3-0 Lionel Andres Messi (2), Jordi Alba | Elche |
| ROUND 2 | |||
| 18.09.20 22:00 | Getafe | 1-0 Jaime Mata | Osasuna |
| 19.09.20 17:00 | Villarreal | 2-1 Gerard Moreno, Paco Alcacer / Kile | Eibar |
| 19.09.20 22:00 | Celta Vigo | 2-1 Iago Aspas (2) / Maxi Gomez | Valencia |
| 20.09.20 17:00 | Huesca | 0-2 Alvaro Negredo,Jorge Pombo | Cadiz |
| 20.09.20 19:30 | Granada CF | 2-1 Roberto Soldado , Darwin Machis / Joselu | Alaves |
| 21.09.20 22:00 | Real Betis | 2-0 Nabil Fekir, William Carvalho | Valladolid |
| 20.09.20 22:00 | Real Sociedad | 0-0 | Real Madrid |
| 06-01-21 22:00 | Athletic Club | 2-3 Inaki Williams, Iker Muniain / Pedri, Lionel Andres Messi (2) | Barcelona |
| 17-02-21 22:00 | Levante | 1-1 Enis Bardhi / Marcos Llorente | Atletico Madrid |
| Sevilla | - | Elche | |
| 27.09.20 18:00 | Alaves | 0-0 | Getafe |
| 27.09.20 18:00 | Valencia | 1-1 Daniel Wass / Dimitris Siovas | Huesca |
| 27.09.20 18:00 | Elche | 0-3 Cristian Portu, Adnan Januzaj, Roberto Lopez | Real Sociedad |
| 27.09.20 18:00 | Real Betis | 2-3 Aissa Mandi, William Carvalho / Federico Valverde, Emerson (og), Sergio Ramos | Real Madrid |
| 27.09.20 18:00 | Atletico Madrid | 6-1 Diego Costa, Angel Correa , Joao Felix, Marcos Llorente, Luis Suarez (2) / Jorge Molina | Granada CF |
| 27.09.20 18:00 | Barcelona | 4-0 Ansu Fati (2), Lionel Andres Messi, Pau Torres (og) | Villarreal |
| 27.09.20 18:00 | Cadiz | 1-3 Salvi / Luuk de Jong, Ivan Rakitic, Munir El Haddadi | Sevilla |
| 27.09.20 18:00 | Eibar | 1-2 Kike / Unai Lopez (2) | Athletic Club |
| 27.09.20 18:00 | Osasuna | 1-3 Roberto Torres / Gonzalo Melero, Roger Marti, Jose Luis Morales | Levante |
| 27.09.20 18:00 | Valladolid | 1-1 Sergi Guardiola / Iago Aspas | Celta Vigo |
| ROUND 4 | |||
| 29.09.20 18:00 | Getafe | 3-0 Angel Rodriguez (2), Marc Cucurella | Real Betis |
| 29.09.20 18:00 | Real Sociedad | 0-1 Maxi Gomez | Valencia |
| 30.09.20 18:00 | Eibar | 0-1 Lucas Boye | Elche |
| 30.09.20 18:00 | Real Madrid | 1-0 Vinicius Junior | Valladolid |
| 30.09.20 18:00 | Villarreal | 3-1 Paco Alcacer (2), Gerard Moreno / Edgar Mendez | Alaves |
| 30.09.20 18:00 | Huesca | 0-0 | Atletico Madrid |
| 01-10.20 18:00 | Athletic Club | 0-1 Unai Lopez (og) | Cadiz |
| 01-10.20 18:00 | Sevilla | 1-0 Youssef En-Nesyri | Levante |
| 01-10.20 18:00 | Celta Vigo | 0-3 Ansu Fati, Lucas Olaza (og), Sergi Roberto | Barcelona |
| 12-01-2021 | Granada CF | 2-0 Luis Suarez, Sergio Herrera (og) | Osasuna |
| ROUND 5 | |||
| 03.10.20 18:00 | Atletico Madrid | 0-0 | Villarreal |
| 03.10.20 18:00 | Valencia | 0-2 Sergio Canales, Cristian Tello | Real Betis |
| 03.10.20 18:00 | Real Socieda | 3-0 Mikel Oyarzabal, Mikel Merino, Cristian Portu | Getafe |
| 03.10.20 18:00 | Elche | 0-0 | Huesca |
| 03.10.20 18:00 | Valladolid | 1-2 Toni Villa / Esteban Burgos, Kevin Rodrigues | Eibar |
| 04.10.20 18:00 | Levante | 0-2 Vinicius Junior, Karim Benzema | Real Madrid |
| 04.10.20 18:00 | Alaves | 1-0 Rodrigo Ely | Athletic Club |
| 04.10.20 18:00 | Cadiz | 1-1 Ivan Alejo / German Sanchez | Granada CF |
| 04.10.20 18:00 | Osasuna | 2-0 Facundo Roncaglia, Jonathan Calleri | Celta Vigo |
| 04.10.20 18:00 | Barcelona | 1-1 Philippe Coutinho / Luuk de Jong | Sevilla |
| ROUND 6 | |||
| 17.10.20 18:00 | Celta Vigo | 0-2 Luis Suarez, Yannick Ferreira-Carrasco | Atletico Madrid |
| 17.10.20 18:00 | Granada CF | 1-0 Yangel Herrera | Sevilla |
| 17.10.20 18:00 | Real Madrid | 0-1 Anthony Lozano | Cadiz |
| 17.10.20 18:00 | Getafe | 1-0 Jaime Mata | Barcelona |
| 18.10.20 18:00 | Eibar | 0-0 | Osasuna |
| 18.10.20 18:00 | Athletic Club | 2-0 Alex Berenguer, Inaki Williams | Levante |
| 18.10.20 18:00 | Alaves | 0-2 Pere Milla, Tete Morente | Elche |
| 18.10.20 18:00 | Villarreal | 2-1 Paco Alcacer , Dani Parejo / Goncalo Guedes | Valencia |
| 18.10.20 18:00 | Huesca | 2-2 Rafa Mir, Sandro Ramirez / Bruno Gonzalez, Waldo Rubio | Valladolid |
| 18.10.20 18:00 | Real Betis | 0-3 Cristian Portu, Mikel Oyarzabal, Adnan Januzaj | Real Sociedad |
| ROUND 7 | |||
| 23.10.20 19:00 | Elche | 2-1 Josan, Fidel / Lato Toni | Valencia |
| 24.10.20 19:00 | Atletico Madrid | 2-0 Marcos Llorente, Luis Suarez | Real Betis |
| 24.10.20 19:00 | Barcelona | 1-3 Ansu Fati / Federico Valverde, Sergio Ramos, Luka Modric | Real Madrid |
| 24.10.20 19:00 | Osasuna | 1-0 Ruben Garcia | Athletic Club |
| 24.10.20 19:00 | Sevilla | 0-1 Kike | Eibar |
| 25.10.20 19:00 | Cadiz | 0-0 | Villarreal |
| 25.10.20 19:00 | Valladolid | 0-2 Tomas Pina, Borja Sainz | Alaves |
| 25.10.20 19:00 | Getafe | 0-1 Angel Montoro | Granada CF |
| 25.10.20 19:00 | Real Sociedad | 4-1 Mikel Oyarzabal, Cristian Portu, Aleksander Isak / Rafa Mir | Huesca |
| 25.10.20 19:00 | Levante | 1-1 Roger Marti / Carreira Sergio Vilarino | Celta Vigo |
| ROUND 8 | |||
| 30.10.20 19:00 | Eibar | 0-2 Alvaro Negredo, Salvi | Cadiz |
| 31.10.20 | Real Madrid | 4-1 Eden Hazard, Karim Benzema (2), Federico Valverde / David Ferreiro | Huesca |
| 31.10.20 | Athletic Club | 2-1 Iker Muniain, Oihan Sancet / Youssef En-Nesyri | Sevilla |
| 31.10.20 | Osasuna | 1-3 Ante Budimir / Joao Felix (2), Lucas Torreira | Atletico Madrid |
| 31.10.20 | Alaves | 1-1 Luis Rioja / Antoine Griezmann | Barcelona |
| 01.11.20 19:00 | Celta Vigo | 1-4 Iago Aspas / David Silva, Mikel Oyarzabal, Willian Jose (2) | Real Sociedad |
| 01.11.20 19:00 | Granada CF | 1-1 Darwin Machis / Ruben Vezo | Levante |
| 01.11.20 19:00 | Real Betis | 3-1 Antonio Sanabria, Cristian Tello (2) / Josan | Elche |
| 01.11.20 19:00 | Valencia | 2-2 Yunus Musah, Carlos Soler / Cucho Hernandez, Angel Rodriguez | Getafe |
| 02.11.20 19:00 | Villarreal | 2-0 Samuel Chimerenka Chukweze, Pau Torres | Valladolid |
| ROUND 9 | |||
| 06.11.20 19:00 | Elche | 1-1 Fidel / Santi Mina | Celta Vigo |
| 07.11.20 19:00 | Atletico Madrid | 4-0 Joao Felix (2), Marcos Llorente, Luis Suarez | Cadiz |
| 07.11.20 19:00 | Huesca | 1-1 Rafa Mir / Esteban Burgos | Eibar |
| 07.11.20 19:00 | Sevilla | 1-0 Lucas Ocampos | Osasuna |
| 07.11.20 19:00 | Barcelona | 5-2 Ousmane Dembele, Antoine Griezmann, Lionel Andres Messi (2), Pedri / Antonio Sanabria, Loren Moron | Real Betis |
| 08.11.20 19:00 | Getafe | 1-3 Mauro Arambarri / Paco Alcacer, Manu Trigueros, Gerard Moreno | Villarreal |
| 08.11.20 19:00 | Levante | 1-1 Jose Luis Morales / Lucas Perez | Alaves |
| 08.11.20 19:00 | Real Sociedad | 2-0 Nacho Monreal, Mikel Oyarzabal | Granada CF |
| 08.11.20 19:00 | Valencia | 4-1 Carlos Soler (3), Raphael Varane (og) / Karim Benzema | Real Madrid |
| 08.11.20 19:00 | Valladolid | 2-1 Fabian Orellana, Marcos De Sousa / Inaki Williams | Athletic Club |
| ROUND 10 | |||
| 20.11.20 19:00 | Osasuna | 1-1 David Garcia / Sandro Ramirez | Huesca |
| 21.11.20 19:00 | Levante | 1-1 Gonzalo Melero / Tete Morente | Elche |
| 21.11.20 19:00 | Atletico Madrid | 1-0 Yannick Ferreira-Carrasco | Barcelona |
| 21.11.20 19:00 | Sevilla | 4-2 Jules Kounde, Youssef En-Nesyri, Sergio Escudero, Munir El Haddadi / Iago Aspas, Nolito | Celta Vigo |
| 21.11.20 19:00 | Villarreal | 1-1 Gerard Moreno / Mariano Diaz | Real Madrid |
| 22.11.20 19:00 | Cadiz | 0-1 Aleksander Isak | Real Sociedad |
| 22.11.20 19:00 | Eibar | 0-0 | Getafe |
| 22.11.20 19:00 | Granada CF | 1-3 Domingos Duarte / Oscar Plano, Marcos De Sousa, Jota | Valladolid |
| 22.11.20 19:00 | Alaves | 2-2 Ximo Navarro, Lucas Perez / Manu Vallejo, Hugo Guillamon | Valencia |
| 22.11.20 19:00 | Athletic Club | 4-0 Victor Ruiz (og), 9' Ander Capa, Iker Muniain, Alex Berenguer | Real Betis |
| ROUND 11 | |||
| 27.11.20 19:00 | Valladolid | 1-1 Marcos De Sousa / Jose Campana | Levante |
| 28.11.20 19:00 | Real Madrid | 1-2 Casemiro / Lucas Perez, Joselu | Alaves |
| 28.11.20 19:00 | Valencia | 0-1 Lato Toni (og) | Atletico Madrid |
| 28.11.20 19:00 | Huesca | 0-1 Youssef En-Nesyri | Sevilla |
| 28.11.20 19:00 | Elche | 1-1 Lucas Boye / Alvaro Gimenez | Cadiz |
| 29.11.20 19:00 | Celta Vigo | 3-1 Nolito, Miguel Baeza, Fran Beltran / Luis Suarez | Granada CF |
| 29.11.20 19:00 | Getafe | 1-1 Angel Rodriguez / Asier Villalibre | Athletic Club |
| 29.11.20 19:00 | Barcelona | 4-0 Martin Braithwaite, Antonie Griezmann, Philippe Coutinho, Lionel Andres Messi | Osasuna |
| 29.11.20 19:00 | Real Sociedad | 1-1 Mikel Oyarzabal / Gerard Moreno | Villarreal |
| 30.11.20 19:00 | Real Betis | 0-2 Yoshinori Muto, Esteban Burgos | Eibar |
| ROUND 12 | |||
| 04.12.20 19:00 | Athletic Club | 0-2 Hugo Mallo, Iago Aspas | Celta Vigo |
| 05.12.20 19:00 | Sevilla | 0-1 Bono (og) | Real Madrid |
| 05.12.20 19:00 | Levante | 3-0 Roger Marti, Dani Gomez, Jorge De Frutos Sebastian | Getafe |
| 05.12.20 19:00 | Atletico Madrid | 2-0 Marcos Llorente (2) | Valladolid |
| 05.12.20 19:00 | Cadiz | 2-1 Alvaro Gimenez, Alvaro Negredo / Pedro Alcala (og) | Barcelona |
| 06.12.20 19:00 | Alaves | 0-0 | Real Sociedad |
| 06.12.20 19:00 | Granada CF | 3-3 Luis Suarez, Jorge Molina, German Sanchez / Mikel Rico, Borja Garcia, Shinji Okazaki | Huesca |
| 06.12.20 19:00 | Osasuna | 0-2 Borja Iglesias, Juan Miranda | Real Betis |
| 07.12.20 19:00 | Villarreal | 0-0 | Elche |
| 06.12.20 19:00 | Eibar | 0-0 | Valencia |
| ROUND 13 | |||
| 11.12.20 19:00 | Valladolid | 3-2 Shon Weissman (2), Fabian Orellana / Ante Budimir, Roberto Torres | Osasuna |
| 12.12.20 19:00 | Valencia | 2-2 Carlos Soler, Manu Vallejo / Asier Villalibre, Raul Garcia | Athletic Club |
| 12.12.20 19:00 | Huesca | 1-0 Javier Ontiveros | Alaves |
| 12.12.20 19:00 | Getafe | 0-1 Xabier Etxeita (og) | Sevilla |
| 12.12.20 19:00 | Real Madrid | 2-0 Casemiro, Jan Oblak (og) | Atletico Madrid |
| 13.12.20 19:00 | Elche | 0-1 Luis Suarez | Granada CF |
| 13.12.20 19:00 | Real Betis | 1-1 Aitor Ruibal / Pau Torres | Villarreal |
| 13.12.20 19:00 | Real Sociedad | 1-1 Ander Barrenetxea / Sergi Enrich | Eibar |
| 13.12.20 19:00 | Barcelona | 1-0 Lionel Andres Messi | Levante |
| 14.12.20 19:00 | Celta Vigo | - | Cadiz |
| ROUND 19 | |||
| 16.12.20 19:00 | Real Madrid | 3-1 Toni Kroos, Karim Benzema (2) / Ander Capa | Athletic Club |
| 16.12.20 19:00 | Barcelona | 2-1 Jordi Alba, Frenkie de Jong / Willian Jose | Real Sociedad |
| ROUND 14 | |||
| 18.12.20 19:00 | Athletic Club | 2-0 Kenan Kodro, Unai Nunez | Huesca |
| 19.12.20 19:00 | Atletico Madrid | 3-1 Luis Suarez (2), Diego Costa / Lucas Boye | Elche |
| 19.12.20 19:00 | Barcelona | 2-2 Lionel Andres Messi, Ronald Araujo / Mouctar Diakhaby, Maxi Gomez | Valencia |
| 19.12.20 19:00 | Osasuna | 1-3 Roberto Torres / Gerard Moreno (2), Fer Nino | Villarreal |
| 19.12.20 19:00 | Levante | 2-1 Roger Marti, Jorge De Frutos Sebastian / Aleksander Isak | Real Sociedad |
| 19.12.20 19:00 | Sevilla | 1-1 Lucas Ocampos / Raul Garcia | Valladolid |
| 20.12.20 19:00 | Cadiz | 0-2 Cucho Hernandez, Nemanja Maksimovic | Getafe |
| 20.12.20 19:00 | Celta Vigo | 2-0 Brais Mendez (2) | Alaves |
| 20.12.20 19:00 | Eibar | 1-3 Kike / Karim Benzema, Luka Modric, Lucas Vazquez | Real Madrid |
| 20.12.20 19:00 | Granada CF | 2-0 Roberto Soldado (2) | Real Betis |
| ROUND 15 | |||
| 22.12.20 19:00 | Huesca | 1-1 Javier Ontiveros / Gonzalo Melero | Levante |
| 22.12.20 19:00 | Valencia | 0-1 Suso | Sevilla |
| 22.12.20 19:00 | Elche | 2-2 Fidel, Guido Carrillo / Ruben Garcia, Darko Brasanac | Osasuna |
| 22.12.20 19:00 | Real Sociedad | 0-2 Mario Hermoso, Marcos Llorente | Atletico Madrid |
| 22.12.20 19:00 | Villarreal | 1-1 Yeremi Pino / Inaki Williams | Athletic Club |
| 22.12.20 19:00 | Valladolid | 0-3 Clement Lenglet, Martin Braithwaite, Lionel Andres Messi | Barcelona |
| 23.12.20 19:00 | Getafe | 1-1 Damian Suarez / Iago Aspas | Celta Vigo |
| 23.12.20 19:00 | Real Madrid | 2-0 Casemiro, Karim Benzema | Granada CF |
| 23.12.20 19:00 | Real Betis | 1-0 Guido Rodriguez | Cadiz |
| 23.12.20 19:00 | Alaves | 2-1 Edgar Mendez, Deyverson / Pedro Leon | Eibar |
| ROUND 16 | |||
| 29.12.20 19:00 | Sevilla | 2-0 Lucas Ocampos, Youssef En-Nesyri | Villarreal |
| 29.12.20 19:00 | Levante | 4-3 Oscar Duarte, Jose Luis Morales (2), Roger Marti / Aissa Mandi, Sergio Canales (2) | Real Betis |
| 29.12.20 19:00 | Barcelona | 1-1 Ousmane Dembele / Kike | Eibar |
| 29.12.20 19:00 | Cadiz | 0-0 | Valladolid |
| 30.12.20 19:00 | Granada CF | 2-1 Kenedy, Jorge Molina / Kevin Gameiro | Valencia |
| 30.12.20 19:00 | Atletico Madrid | 1-0 Luis Suarez | Getafe |
| 30.12.20 19:00 | Celta Vigo | 2-1 Nolito, Iago Aspas / Jaime Seoane | Huesca |
| 30.12.20 19:00 | Elche | 1-1 Fidel / Luka Modric | Real Madrid |
| 31.12.20 19:00 | Athletic Club | 0-1 Cristian Portu | Real Sociedad |
| 31.12.20 19:00 | Osasuna | 1-1 Roberto Torres / Lucas Perez | Alaves |
| ROUND 17 | |||
| 02.01.2021 | Villarreal | 2-1 Fer Nino, Gerard Moreno / Sergio Leon | Levante |
| 02.01.2021 | Getafe | 0-1 Shon Weissman | Valladolid |
| 02.01.2021 | Real Betis | 1-1 Sergio Canales / Suso | Sevilla |
| 02.01.2021 | Real Madrid | 2-0 Lucas Vazquez, Marco Asensio | Celta Vigo |
| 03.01.2021 | Alaves | 1-2 Felipe (og) / Marcos Llorente, Luis Suarez | Atletico Madrid |
| 03.01.2021 | Athletic Club | 1-0 Iker Muniain | Elche |
| 03.01.2021 | Eibar | 2-0 Bryan Salvatierra, Edu Exposito | Granada CF |
| 03.01.2021 | Real Sociedad | 1-1 Ander Barrenetxea / Jonathan Calleri | Osasuna |
| 03.01.2021 | Huesca | 0-1 Frenkie de Jong | Barcelona |
| 04.01.2021 | Valencia | 1-1 Maxi Gomez / Anthony Lozano | Cadiz |
| ROUND 2 | |||
| 06.01.21 19:00 | Athletic Club | - | Barcelona |
| ROUND 18 | |||
| 08.01.21 19:00 | Celta Vigo | 0-4 Gerard Moreno, Moi Gomez, Dani Parejo, Fer Nino | Villarreal |
| 09.01.21 19:00 | Granada CF | 0-4 Antoine Griezmann (2), Lionel Andres Messi (2) | Barcelona |
| 09.01.21 19:00 | Sevilla | 3-2 Youssef En-Nesyri (3) / Diego Carlos (og), Aleksander Isak | Real Sociedad |
| 09.01.21 19:00 | Osasuna | 0-0 | Real Madrid |
| 10.01.21 19:00 | Cadiz | 3-1 Alex, Anthony Lozano, Alvaro Negredo / Joselu | Alaves |
| 10.01.21 19:00 | Levante | 2-1 Gonzalo Melero, Jose Luis Morales / Takashi Inui | Eibar |
| 10.01.21 19:00 | Valladolid | 0-1 Carlos Soler | Valencia |
| 11.01.21 19:00 | Huesca | 0-2 Aissa Mandi, Antonio Sanabria | Real Betis |
| 11.01.21 19:00 | Elche | 1-3 Raul Guti / Marc Cucurella, Jaime Mata, Angel Rodriguez | Getafe |
| Atletico Madrid | - | Athletic Club | |
| ROUND 19 | |||
| 1901.21 19:00 | Valladolid | 2-2 Michel, Joaquin Fernandez / Josan (2) | Elche |
| 20.01.21 19:00 | Alaves | 1-2 Edgar Mendez / Youssef En-Nesyri, Suso | Sevilla |
| 19.01.21 19:00 | Cadiz | 2-2 Alberto Perea, Juan Cala / Roger Marti (2) | Levante |
| 20.01.21 19:00 | Real Betis | 2-1 Sergio Canales (2) / Santi Mina | Celta Vigo |
| 20.01.21 19:00 | Villarreal | 2-2 Ruben Pena, Moi Gomez / Roberto Soldado, Kenedy | Granada CF |
| 20.01.21 19:00 | Getafe | 1-0 Mauro Arambarri | Huesca |
| 21.01.21 19:00 | Valencia | 1-1 Unai Garcia (og) / Jonathan Calleri | Osasuna |
| 21.01.21 19:00 | Eibar | 1-2 Marko Dmitrovic / Luis Suarez (2) | Atletico Madrid |
| ROUND 20 | |||
| 22.01.21 19:00 | Levante | 2-2 Dani Gomez, Roger Marti / Ruben Alcaraz, Oscar Plano | Valladolid |
| 23.01.21 19:00 | Real Sociedad | 2-2 Aleksander Isak, Mikel Oyarzabal / Sergio Canales, Joaquin | Real Betis |
| 23.01.21 19:00 | Huesca | 0-0 | Villarreal |
| 23.01.21 19:00 | Sevilla | 3-0 Youssef En-Nesyri (3) | Cadiz |
| 23.01.21 19:00 | Alaves | 1-4 Joselu / Casemiro, Karim Benzema (2), Eden Hazard | Real Madrid |
| 24.01.21 19:00 | Atletico Madrid | 3-1 Joao Felix, Luis Suarez, Angel Correa / Uros Racic | Valencia |
| 24.01.21 19:00 | Celta Vigo | 1-1 Brais Mendez / Bryan Salvatierra | Eibar |
| 24.01.21 19:00 | Elche | 0-2 Frenkie de Jong, Riqui Puig | Barcelona |
| 24.01.21 19:00 | Osasuna | 3-1 Ante Budimir (2), Jon Moncayola / Luis Suarez | Granada CF |
| 25.01.21 19:00 | Athletic Club | 5-1 Raul Garcia (2), Yeray Alvarez, Alex Berenguer, Oscar de Marcos / Marc Cucurella | Getafe |
| ROUND 21 | |||
| 29.01.21 19:00 | Valladolid | 1-3 Toni Villa / Rafa Mir (3) | Huesca |
| 30.01.21 19:00 | Eibar | 0-2 Lucas Ocampos, Joan Jordan | Sevilla |
| 30.01.21 19:00 | Valencia | 1-0 Daniel Wass | Elche |
| 30.01.21 19:00 | Real Madrid | 1-2 Marco Asensio / Jose Luis Morales, Roger Marti | Levante |
| 30.01.21 19:00 | Villarreal | 1-1 Dani Parejo / Aleksander Isak | Real Sociedad |
| 31.01.21 19:00 | Getafe | 0-0 | Alaves |
| 31.01.21 19:00 | Granada CF | 0-0 | Celta Vigo |
| 31.01.21 19:00 | Cadiz | 2-4 Alvaro Negredo (2) / Saul, Luis Suarez (2), Koke | Atletico Madrid |
| 31.01.21 19:00 | Barcelona | 2-1 Lionel Andres Messi, Antoine Griezmann / Jordi Alba (og) | Athletic Club |
| 01.02.21 19:00 | Real Betis | 1-0 Borja Iglesias | Osasuna |
| ROUND 22 | |||
| 05.02.21 19:00 | Alaves | 1-0 Joselu | Valladolid |
| 06.02.21 19:00 | Elche | 2-2 Guido Carrillo, Lucas Boye / Gerard Moreno (2) | Villarreal |
| 06.02.21 19:00 | Levante | 2-2 Jose Luis Morales (2) / Kenedy, Roberto Soldado | Granada CF |
| 06.02.21 19:00 | Huesca | 1-2 Javi Galan / Raphael Varane (2) | Real Madrid |
| 06.02.21 19:00 | Sevilla | 3-0 Munir El Haddadi, Papu Gomez, Youssef En-Nesyri | Getafe |
| 07.02.21 19:00 | Athletic Club | 1-1 Hugo Guillamon (og) / Gabriel Paulista | Valencia |
| 07.02.21 19:00 | Osasuna | 2-1 Jonathan Calleri, Ante Budimir / Kike | Eibar |
| 07.02.21 19:00 | Real Betis | 2-3 Borja Iglesias, Victor Ruiz / Lionel Andres Messi, Victor Ruiz (og), Francisco Trincao | Barcelona |
| 07.02.21 19:00 | Real Sociedad | 4-1 Mikel Oyarzabal (2), Aleksander Isak (2) / Jairo Izquierdo | Cadiz |
| 08.02.21 19:00 | Atletico Madrid | 2-2 Luis Suarez (2) / Santi Mina, Facundo Ferreyra | Celta Vigo |
| ROUND 23 | |||
| 12.02.21 19:00 | Celta Vigo | 3-1 Brais Mendez, Santi Mina (2) / Emiliano Rigoni | Elche |
| 13.02.21 19:00 | Eibar | 1-1 Kike / Roque Mesa | Valladolid |
| 13.02.21 19:00 | Granada CF | 1-2 Yangel Herrera / Marcos Llorente, Angel Correa | Atletico Madrid |
| 13.02.21 19:00 | Sevilla | 1-0 Munir El Haddadi | Huesca |
| 13.02.21 19:00 | Barcelona | 5-1 Francisco Trincao (2), Lionel Andres Messi (2), Junior Firpo / Luis Rioja | Alaves |
| 14.02.21 19:00 | Getafe | 0-1 Aleksander Isak | Real Sociedad |
| 14.02.21 19:00 | Levante | 0-1 Ante Budimir | Osasuna |
| 14.02.21 19:00 | Real Madrid | 2-0 Karim Benzema, Toni Kroos | Valencia |
| 14.02.21 19:00 | Villarreal | 1-2 Gerard Moreno / Nabil Fekir, Emerson | Real Betis |
| 15.02.21 19:00 | Cadiz | 0-4 Unai Lopez, Alex Berenguer (2), Inaki Williams | Athletic Club |
| ROUND 24 | |||
| 19.02.21 19:00 | Real Betis | 1-0 Borja Iglesias | Getafe |
| 20.02.21 19:00 | Atletico Madrid | 0-2 Jose Luis Morales, Jorge De Frutos Sebastian | Levante |
| 20.02.21 19:00 | Elche | 1-0 Dani Calvo | Eibar |
| 20.02.21 19:00 | Valencia | 2-0 Kevin Gameiro , Manu Vallejo | Celta Vigo |
| 20.02.21 19:00 | Valladolid | 0-1 Casemiro | Real Madrid |
| 21.02.21 19:00 | Huesca | 3-2 Dani Escriche, Jorge Pulido, Dimitri Foulquier / Domingos Quina, Alberto Soro | Granada CF |
| 21.02.21 19:00 | Athletic Club | 1-1 Alex Berenguer / Gerard Moreno | Villarreal |
| 21.02.21 19:00 | Barcelona | 1-1 Lionel Andres Messi / Alex | Cadiz |
| 21.02.21 19:00 | Real Sociedad | 4-0 Aleksander Isak (3), Cristian Portu | Alaves |
| 22.02.21 19:00 | Osasuna | 0-2 Diego Carlos, Luuk de Jong | Sevilla |
| ROUND 25 | |||
| 28.02.21 19:00 | Alaves | - | Osasuna |
| 28.02.21 19:00 | Cadiz | - | Real Betis |
| 28.02.21 19:00 | Celta Vigo | - | Valladolid |
| 28.02.21 19:00 | Eibar | - | Huesca |
| 28.02.21 19:00 | Getafe | - | Valencia |
| 28.02.21 19:00 | Granada CF | - | Elche |
| 28.02.21 19:00 | Levante | - | Athletic Club |
| 28.02.21 19:00 | Real Madrid | - | Real Sociedad |
| 28.02.21 19:00 | Sevilla | - | Barcelona |
| 28.02.21 19:00 | Villarreal | - | Atletico Madrid |
| ROUND 26 | |||
| 07.03.21 19:00 | Athletic Club | - | Granada CF |
| 07.03.21 19:00 | Atletico Madrid | - | Real Madrid |
| 07.03.21 19:00 | Cadiz | - | Eibar |
| ROUND 26 | |||
| 07.03.21 19:00 | Elche | - | Sevilla |
| 07.03.21 19:00 | Huesca | - | Celta Vigo |
| 07.03.21 19:00 | Osasuna | - | Barcelona |
| 07.03.21 19:00 | Real Betis | - | Alaves |
| 07.03.21 19:00 | Real Sociedad | - | Levante |
| 07.03.21 19:00 | Valencia | - | Villarreal |
| 07.03.21 19:00 | Valladolid | - | Getafe |
| ROUND 27 | |||
| 14.03.21 19:00 | Alaves | - | Cadiz |
| 14.03.21 19:00 | Barcelona | - | Huesca |
| 14.03.21 19:00 | Celta Vigo | - | Athletic Club |
| 14.03.21 19:00 | Eibar | - | Villarreal |
| 14.03.21 19:00 | Getafe | - | Atletico Madrid |
| 14.03.21 19:00 | Granada CF | - | Real Sociedad |
| 14.03.21 19:00 | Levante | - | Valencia |
| 14.03.21 19:00 | Osasuna | - | Valladolid |
| 14.03.21 19:00 | Real Madrid | - | Elche |
| 14.03.21 19:00 | Sevilla | - | Real Betis |
| ROUND 28 | |||
| 21.03.21 19:00 | Athletic Club | - | Eibar |
| 21.03.21 19:00 | Atletico Madrid | - | Alaves |
| 21.03.21 19:00 | Celta Vigo | - | Real Madrid |
| 21.03.21 19:00 | Getafe | - | Elche |
| 21.03.21 19:00 | Huesca | - | Osasuna |
| 21.03.21 19:00 | Real Betis | - | Levante |
| 21.03.21 19:00 | Real Sociedad | - | Barcelona |
| 21.03.21 19:00 | Valencia | - | Granada CF |
| 21.03.21 19:00 | Valladolid | - | Sevilla |
| 21.03.21 19:00 | Villarreal | - | Cadiz |
| ROUND 29 | |||
| 04.04.21 18:00 | Alaves | - | Celta Vigo |
| 04.04.21 18:00 | Barcelona | - | Valladolid |
| 04.04.21 18:00 | Cadiz | - | Valencia |
| 04.04.21 18:00 | Elche | - | Real Betis |
| 04.04.21 18:00 | Granada CF | - | Villarreal |
| 04.04.21 18:00 | Levante | - | Huesca |
| 04.04.21 18:00 | Osasuna | - | Getafe |
| 04.04.21 18:00 | Real Madrid | - | Eibar |
| 04.04.21 18:00 | Real Sociedad | - | Athletic Club |
| 04.04.21 18:00 | Sevilla | - | Atletico Madrid |
| ROUND 30 | |||
| 11.04.21 18:00 | Athletic Club | - | Alaves |
| 11.04.21 18:00 | Celta Vigo | - | Sevilla |
| 11.04.21 18:00 | Eibar | - | Levante |
| 11.04.21 18:00 | Getafe | - | Cadiz |
| 11.04.21 18:00 | Huesca | - | Elche |
| 11.04.21 18:00 | Real Betis | - | Atletico Madrid |
| 11.04.21 18:00 | Real Madrid | - | Barcelona |
| 11.04.21 18:00 | Valencia | - | Real Sociedad |
| 11.04.21 18:00 | Valladolid | - | Granada CF |
| 11.04.21 18:00 | Villarreal | - | Osasuna |
| ROUND 31 | |||
| 21.04.21 18:00 | Alaves | - | Villarreal |
| 21.04.21 18:00 | Atletico Madrid | - | Huesca |
| 21.04.21 18:00 | Barcelona | - | Getafe |
| ROUND 31 | |||
| 21.04.21 18:00 | Cadiz | - | Real Madrid |
| 21.04.21 18:00 | Elche | - | Valladolid |
| 21.04.21 18:00 | Granada CF | - | Eibar |
| 21.04.21 18:00 | Levante | - | Sevilla |
| 21.04.21 18:00 | Osasuna | - | Valencia |
| 21.04.21 18:00 | Real Betis | - | Athletic Club |
| 21.04.21 18:00 | Real Sociedad | - | Celta Vigo |
| ROUND 32 | |||
| 25.04.21 18:00 | Athletic Club | - | Atletico Madrid |
| 25.04.21 18:00 | Celta Vigo | - | Osasuna |
| 25.04.21 18:00 | Eibar | - | Real Sociedad |
| 25.04.21 18:00 | Elche | - | Levante |
| 25.04.21 18:00 | Huesca | - | Getafe |
| 25.04.21 18:00 | Real Madrid | - | Real Betis |
| 25.04.21 18:00 | Sevilla | - | Granada CF |
| 25.04.21 18:00 | Valencia | - | Alaves |
| 25.04.21 18:00 | Valladolid | - | Cadiz |
| 25.04.21 18:00 | Villarreal | - | Barcelona |
| ROUND 33 | |||
| 28.04.21 18:00 | Alaves | - | Huesca |
| 28.04.21 18:00 | Athletic Club | - | Valladolid |
| 28.04.21 18:00 | Atletico Madrid | - | Eibar |
| 28.04.21 18:00 | Barcelona | - | Granada CF |
| 28.04.21 18:00 | Cadiz | - | Celta Vigo |
| 28.04.21 18:00 | Getafe | - | Real Madrid |
| 28.04.21 18:00 | Levante | - | Villarreal |
| 28.04.21 18:00 | Osasuna | - | Elche |
| 28.04.21 18:00 | Real Betis | - | Valencia |
| 28.04.21 18:00 | Real Sociedad | - | Sevilla |
| ROUND 34 | |||
| 02.05.21 18:00 | Celta Vigo | - | Levante |
| 02.05.21 18:00 | Eibar | - | Alaves |
| 02.05.21 18:00 | Elche | - | Atletico Madrid |
| 02.05.21 18:00 | Granada CF | - | Cadiz |
| 02.05.21 18:00 | Huesca | - | Real Sociedad |
| 02.05.21 18:00 | Real Madrid | - | Osasuna |
| 02.05.21 18:00 | Sevilla | - | Athletic Club |
| 02.05.21 18:00 | Valencia | - | Barcelona |
| 02.05.21 18:00 | Valladolid | - | Real Betis |
| 02.05.21 18:00 | Villarreal | - | Getafe |
| ROUND 35 | |||
| 09.05.21 18:00 | Alaves | - | Levante |
| 09.05.21 18:00 | Athletic Club | - | Osasuna |
| 09.05.21 18:00 | Barcelona | - | Atletico Madrid |
| 09.05.21 18:00 | Cadiz | - | Huesca |
| 09.05.21 18:00 | Getafe | - | Eibar |
| 09.05.21 18:00 | Real Betis | - | Granada CF |
| 09.05.21 18:00 | Real Madrid | - | Sevilla |
| 09.05.21 18:00 | Real Sociedad | - | Elche |
| 09.05.21 18:00 | Valencia | - | Valladolid |
| 09.05.21 18:00 | Villarreal | - | Celta Vigo |
| ROUND 36 | |||
| 12.05.21 18:00 | Atletico Madrid | - | Real Sociedad |
| 12.05.21 18:00 | Celta Vigo | - | Getafe |
| 12.05.21 18:00 | Eibar | - | Real Betis |
| ROUND 36 | |||
| 12.05.21 18:00 | Elche | - | Alaves |
| 12.05.21 18:00 | Granada CF | - | Real Madrid |
| 12.05.21 18:00 | Huesca | - | Athletic Club |
| 12.05.21 18:00 | Levante | - | Barcelona |
| 12.05.21 18:00 | Osasuna | - | Cadiz |
| 12.05.21 18:00 | Sevilla | - | Valencia |
| 12.05.21 18:00 | Valladolid | - | Villarreal |
| ROUND 37 | |||
| 16.05.21 18:00 | Alaves | - | Granada CF |
| 16.05.21 18:00 | Athletic Club | - | Real Madrid |
| 16.05.21 18:00 | Atletico Madrid | - | Osasuna |
| 16.05.21 18:00 | Barcelona | - | Celta Vigo |
| 16.05.21 18:00 | Cadiz | - | Elche |
| 16.05.21 18:00 | Getafe | - | Levante |
| 16.05.21 18:00 | Real Betis | - | Huesca |
| 16.05.21 18:00 | Real Sociedad | - | Valladolid |
| 16.05.21 18:00 | Valencia | - | Eibar |
| 16.05.21 18:00 | Villarreal | - | Sevilla |
| ROUND 38 | |||
| 23.05.21 18:00 | Celta Vigo | - | Real Betis |
| 23.05.21 18:00 | Eibar | - | Barcelona |
| 23.05.21 18:00 | Elche | - | Athletic Club |
| 23.05.21 18:00 | Granada CF | - | Getafe |
| 23.05.21 18:00 | Huesca | - | Valencia |
| 23.05.21 18:00 | Levante | - | Cadiz |
| 23.05.21 18:00 | Osasuna | - | Real Sociedad |
| 23.05.21 18:00 | Real Madrid | - | Villarreal |
| 23.05.21 18:00 | Sevilla | - | Alaves |
| 23.05.21 18:00 | Valladolid | - | Atletico Madrid |
